Assistance Publique Hôpitaux de Paris (AP-HP), Hospitalisation À Domicile (HAD), 14 rue Vésale, 75005, Paris, France.
Assistance Publique Hôpitaux de Paris (AP-HP), Centre National de Référence en Hémobiologie Périnatale (CNRHP), 26 avenue du Dr Arnold-Netter, 75571, Paris, France.
Eur J Pediatr. 2022 Aug;181(8):3075-3084. doi: 10.1007/s00431-022-04461-4. Epub 2022 Jun 13.
Neonatal jaundice is common and associated with delay in hospital discharge and risk of neurological sequelae if not treated. The objectives of the study were to report on our experience of the monitoring and treatment of neonatal jaundice in a home care setting and its feasibility and safety for neonates with high risk of severe hyperbilirubinemia. The 2-year study has been led in the greater Paris University Hospital At Home (Assistance Publique-Hôpitaux de Paris). The device of the intervention was the Bilicocoon® Bag, a light-emitting diode sleeping bag worn by the neonate when the total serum bilirubin value exceeds intensive phototherapy threshold, according to the guidelines from the American Academy of Pediatrics. One hundred and thirty-nine neonates had participated in the intervention and 39 (28%) were treated by phototherapy at home, as continuation of inpatient phototherapy or started at home. Seventy-five percent of the sample had more than two risk factors for development of severe hyperbilirubinemia. Twenty five percent of the cohort who received phototherapy at home had lower gestational age (p < 0.014) and had younger age at discharge from maternity (p < 0.09). Median length of stay in hospital at home was 5 days. Two patients needed readmission in conventional hospital (1%) for less than 24 h. In multivariate model, the length of stay decreased with the higher gestational age (p < 0.001) and increased significantly with the older age at discharge, the birth weight < 10th percentile, and a treatment by phototherapy at home. Conclusion: Hospital at home, which is a whole strategy using an effective and convenient phototherapy device combined with a specialized medical follow-up, could be an alternative to conventional hospitalization for neonates at high risk of severe jaundice. The maternity discharge is facilitated, the mother-infant bonding can be promoted, and the risk of conventional rehospitalization is minimal, while guaranteeing the safety of this specific care. What is Known: • Managing neonatal jaundice is provided in conventional hospital with phototherapy. • Neonatal jaundice increases the risk of prolonged hospitalization or readmission. What is New: • Phototherapy is feasible in hospital at home for neonates with high risk of severe hyperbilirubinemia. • The care pathway of neonates from conventional hospital to hospital at home is described.
新生儿黄疸很常见,如果不治疗,会导致住院时间延长,并可能导致神经后遗症。本研究的目的是报告我们在家庭护理环境中监测和治疗新生儿黄疸的经验,以及对于高风险重度高胆红素血症的新生儿,这种方法的可行性和安全性。这项为期两年的研究是在巴黎公立医院居家医疗服务(Assistance Publique-Hôpitaux de Paris)进行的。干预的设备是 Bilicocoon® Bag,这是一种发光二极管睡袋,当血清总胆红素值超过美国儿科学会指南规定的强化光疗阈值时,新生儿就会穿着它。有 139 名新生儿参与了干预,其中 39 名(28%)在家中接受光疗治疗,或是在住院光疗的基础上继续治疗,或是在家中开始治疗。该样本中有 75%的新生儿有两个或两个以上发展为重度高胆红素血症的风险因素。在家中接受光疗治疗的患儿中,有 25%的患儿胎龄较低(p < 0.014),且从产科出院时年龄较小(p < 0.09)。居家住院的中位数为 5 天。有 2 名患儿(1%)因入住常规医院时间少于 24 小时而需要再次入院。在多变量模型中,随着胎龄的增加(p < 0.001),住院时间缩短,随着出院年龄的增加、出生体重低于第 10 百分位数以及在家中接受光疗治疗,住院时间显著增加。结论:居家医疗服务是一种整体策略,它使用一种有效且方便的光疗设备,结合专业的医疗随访,可以作为高风险重度黄疸新生儿的常规住院治疗的替代方案。它可以促进产妇出院,促进母婴联系,并最大限度地降低常规再入院的风险,同时保证这种特殊护理的安全性。已知内容:• 新生儿黄疸的管理是在常规医院进行的,采用的方法是光疗。• 新生儿黄疸会增加住院时间延长或再次入院的风险。新内容:• 对于高风险重度高胆红素血症的新生儿,在家中进行光疗是可行的。• 描述了将常规医院的新生儿转至居家医疗服务的护理路径。