Suppr超能文献

意大利全国因 COVID-19 疫情封锁期间,在妇产科病房中对新生儿黄疸进行家庭光疗监测的初步研究。

Pilot study of home phototherapy for neonatal jaundice monitored in maternity ward during the enforced Italy-wide COVID-19 national lockdown.

机构信息

Division of Perinatal Medicine, Policlinico Abano Terme, Piazza Colombo 1, 35031, Abano Terme, Italy.

UC San Diego, San Diego, CA, USA.

出版信息

Eur J Pediatr. 2022 Sep;181(9):3523-3529. doi: 10.1007/s00431-022-04557-x. Epub 2022 Jul 15.

Abstract

UNLABELLED

In Italy, where neonatal jaundice treatment is required, it is largely carried out in hospitals. However, it is possible to safely administer home phototherapy (HPT). We report our pilot center's experience of HPT and its potential benefits during the COVID-19-enforced national lockdown. This is an observational study performed at the Policlinic Abano Terme, a suburban hospital that covers a large catchment area near the Euganean Hills in Northeast Italy with around 1000 deliveries per year. HPT was started after regular nursery discharge, and the mothers brought the neonates back to the hospital maternity ward each day to check infants' bilirubin levels, weight, and general state of health, until it was deemed safe to stop. The efficacy of HPT in bilirubin reduction, hospital readmission rates, and parental satisfaction were evaluated. Thirty infants received HPT. In 4 of these infants, HPT was associated with total serum bilirubin (TSB) between 75 and 95 percentile (high-intermediate-risk zone) and in 26 infants HPT was associated with TSB > 95 percentile (high-risk zone) of the Bhutani nomogram. Among these 30 infants, 27 (90%) completed the HPT with a progressive decrease of TSB levels with 4 neonates requiring a second course and 3 infants requiring a third course of 24-h HPT. Three (10%) neonates failed HPT and were readmitted after one 24-h phototherapy course. No abnormalities of breastfeeding, body weight (defined as > 10% decrease), temperature, nor COVID infections were detected following HPT consultation in the neonatal ward. Home treatment efficacy with varying degrees of parental satisfaction occurred in all but 3 cases that involved difficulties with the equipment and inconsistent lamp manipulation practices.

CONCLUSION

Our pilot study suggests that HPT for neonatal jaundice can be carried out effectively and with parental satisfaction as supported by daily back bilirubin monitoring in the maternity ward during the enforced COVID-19 national lockdown in Italy.

WHAT IS KNOWN

• No high-quality evidence is currently available to support or refute the practice of phototherapy in patients' own homes.

WHAT IS NEW

• Phototherapy can be delivered at home in a select group of infants and could be an ideal option if parents are able to return with their infants to the hospital maternity ward for daily follow-up. • It can be as effective as inpatient phototherapy and potentially helps in delivering family-centered care.

摘要

目的

在意大利,新生儿黄疸的治疗需要在医院进行,但也可以安全地进行家庭光疗(HPT)。我们报告了我们的试点中心在 COVID-19 全国封锁期间进行 HPT 的经验及其潜在益处。这是一项在阿巴诺泰尔梅综合诊所(一家郊区医院)进行的观察性研究,该医院覆盖了意大利东北部 Euganean 丘陵附近的一个大的分娩区域,每年约有 1000 名婴儿分娩。HPT 在常规新生儿病房出院后开始进行,母亲每天将新生儿带回医院产科病房检查婴儿的胆红素水平、体重和一般健康状况,直到认为停止治疗是安全的。评估了 HPT 在胆红素降低、住院率和父母满意度方面的效果。30 名婴儿接受了 HPT。其中 4 名婴儿的 HPT 与总血清胆红素(TSB)在 75%至 95%百分位(中高危区)之间有关,26 名婴儿的 HPT 与 Bhutani 列线图的 TSB >95%百分位(高危区)有关。在这 30 名婴儿中,27 名(90%)完成了 HPT,TSB 水平逐渐降低,4 名新生儿需要第二个疗程,3 名婴儿需要第三个 24 小时 HPT 疗程。3 名(10%)婴儿 HPT 失败,在一个 24 小时光疗疗程后再次住院。在新生儿病房进行 HPT 咨询后,没有发现母乳喂养、体重(定义为下降>10%)、体温或 COVID 感染的异常。除了 3 例因设备问题和灯操作不规范导致的治疗困难外,所有病例均在家中有效治疗,且父母满意度不同。

结论

我们的试点研究表明,在意大利 COVID-19 全国封锁期间,在产科病房进行每日背部胆红素监测的情况下,HPT 可以有效地进行,并且可以得到父母的满意。

已知

•目前没有高质量的证据支持或反驳患者在家中接受光疗的做法。

新发现

•光疗可以在一组选定的婴儿中在家中进行,并且如果父母能够带着婴儿返回医院产科病房进行日常随访,这可能是一个理想的选择。•它可以像住院光疗一样有效,并且可能有助于提供以家庭为中心的护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7189/9283816/0c43b5f7c087/431_2022_4557_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验