School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China.
J Food Drug Anal. 2021 Sep 15;29(3):490-501. doi: 10.38212/2224-6614.3360.
A novel magnetic adsorbent solid-phase FeO@ZIF-8 extraction method coupled with UHPLC Q-Orbitrap high resolution mass spectrometry for the sensitive and high efficiency detection of fluoroquinolones, tetracyclines, dyes and amphenicols in eggs is described. Under optimum conditions, CCβ and CCα of 0.62 to 26.97 μg.kg and 0.36 to 16.37 μg.kg was obtained, which is much better than that obtained by conventional methods. The accuracy, expressed as recovery, were achieved falling between 75% and 104%. The proposed strategy provides several advantages of simplicity and low energy consumption, thus retaining potential for the screening of risky drugs in various samples.
本文描述了一种新型的磁性吸附剂固相 FeO@ZIF-8 萃取方法，结合 UHPLC Q-Orbitrap 高分辨率质谱法，用于灵敏、高效地检测鸡蛋中的氟喹诺酮类、四环素类、染料和安普霉素。在最佳条件下，可得到 0.62 至 26.97μg.kg 和 0.36 至 16.37μg.kg 的 CCβ和 CCα，优于常规方法。回收率表示为 75%至 104%之间的准确度。该策略具有简单、低能耗的优点，因此有望用于各种样品中危险药物的筛选。
