Li Wenrui, Ren Nanjiang, Shi Yiheng, Wang Ruihong, Li Guoliang
School of Food Science and Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China.
School of Food Science and Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China.
J Chromatogr A. 2024 Jul 19;1727:464988. doi: 10.1016/j.chroma.2024.464988. Epub 2024 May 10.
In this research, a novel magnetic nanocomposite (FeO@Zn/Al-LABSA-LDH/ZIF-8) was synthesized using FeO as the magnetic core, layered double hydroxide (LDH) with linear alkylbenzene sulfonic acid (LABSA) intercalation and zeolitic imidazolate framework-8 (ZIF-8) as the shell. Benefiting from the intercalation of LABSA into LDH combined with ZIF-8, the multiple interactions, including π-π stacking, hydrogen bonding, and electrostatic interactions, conferred high selectivity and good extraction capability to the material towards heterocyclic aromatic amines (HAAs). FeO@Zn/Al-LABSA-LDH@ZIF-8 was used as an adsorbent for magnetic solid-phase extraction (MSPE) to enrich HAAs in thermally processed meat samples, followed by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) detection. The method exhibited a low detection limit (0.021-0.221 ng/g), good linearity (R ≥ 0.9999), high precision (RSD < 7.2 %), and satisfactory sample recovery (89.7 % -107.5 %). This research provides a promising approach for developing novel adsorbents in sample preparation and improving analytical performance.
在本研究中，以FeO为磁核、层状双氢氧化物（LDH）插层线性烷基苯磺酸（LABSA）并以沸石咪唑酯骨架-8（ZIF-8）为壳层，合成了一种新型磁性纳米复合材料（FeO@Zn/Al-LABSA-LDH/ZIF-8）。得益于LABSA插层到LDH中并与ZIF-8相结合，包括π-π堆积、氢键和静电相互作用在内的多种相互作用赋予了该材料对杂环芳香胺（HAA）的高选择性和良好的萃取能力。FeO@Zn/Al-LABSA-LDH@ZIF-8用作磁性固相萃取（MSPE）的吸附剂，用于富集热处理肉类样品中的HAA，随后进行高效液相色谱-串联质谱（HPLC-MS/MS）检测。该方法具有低检测限（0.021 - 0.221 ng/g）、良好的线性（R≥0.9999）、高精度（RSD<7.2%）和令人满意的样品回收率（89.7% - 107.5%）。本研究为在样品制备中开发新型吸附剂和提高分析性能提供了一种有前景的方法。
