Di Felice Christopher, Alraiyes Abdul H, Gillespie Colin, Machuzak Michael, Gildea Thomas R, Sethi Sonali, Cicenia Joseph, Mehta Atul C, Almeida Francisco A
Division of Pulmonary, Critical Care, and Sleep Medicine, Case Western Reserve University.
Louis Stokes Cleveland Veterans Affairs Medical Center.
J Bronchology Interv Pulmonol. 2023 Jan 1;30(1):54-59. doi: 10.1097/LBR.0000000000000852.
Endoscopic therapies are firmly established in the management algorithm of benign subglottic and tracheal stenosis (SGTS). The optimal dilation strategy, however, has yet to be elucidated. The objective of this study was to compare the efficacy and safety of balloon versus rigid bronchoplasty in the treatment of benign SGTS.
De novo cases of benign SGTS at our institution over a 9-year period were retrospectively identified. Patients were divided into 2 groups based on the initial dilation strategy of balloon or rigid bronchoplasty. Demographics, clinical findings, concurrent interventions, lesion characteristics, and complications were analyzed. Two reviewers independently assigned an index and follow-up endoscopic stenosis grade for each case. The mean stenosis grade at follow-up in both groups was then calculated and compared.
Sixty-three patients with benign SGTS were included. Most stenoses in the rigid (80%) and balloon (63%) bronchoplasty groups were complex ( P =0.174). In addition, 94% (59/63) of index stenoses were classified as Cotton Myer Grade 3. At follow-up, no significant difference was found in the mean stenosis grade between dilation strategies (1.97 vs. 2.2, P =0.287). Furthermore, no procedural-related complications were observed in either group.
Balloon and rigid bronchoplasty are safe and effective endoscopic tools in the early management of benign SGTS. A multimodality approach centered around mucosal sparing techniques remains vitally important to the overall and likely long-term success of treating this challenging disease entity.
内镜治疗在良性声门下及气管狭窄(SGTS)的治疗策略中已得到广泛应用。然而,最佳的扩张策略仍有待阐明。本研究的目的是比较球囊扩张术与硬质支气管成形术治疗良性SGTS的疗效和安全性。
回顾性分析我院9年间新发的良性SGTS病例。根据初始扩张策略将患者分为两组,即球囊扩张术组和硬质支气管成形术组。分析患者的人口统计学资料、临床表现、同期干预措施、病变特征及并发症。两名评估者独立为每个病例指定一个索引和随访内镜下狭窄分级。然后计算并比较两组随访时的平均狭窄分级。
纳入63例良性SGTS患者。硬质支气管成形术组(80%)和球囊扩张术组(63%)的大多数狭窄为复杂性狭窄(P = 0.174)。此外,94%(59/63)的索引狭窄被分类为科顿-迈耶3级。随访时,两种扩张策略的平均狭窄分级无显著差异(1.97对2.2,P = 0.287)。此外,两组均未观察到与手术相关的并发症。
球囊扩张术和硬质支气管成形术是早期治疗良性SGTS安全有效的内镜工具。围绕保留黏膜技术的多模式方法对于成功治疗这一具有挑战性的疾病实体的整体及可能的长期疗效仍然至关重要。