日本正颌手术后抗生素预防时间与手术部位感染的关系。
Association between the duration of antibiotic prophylaxis and surgical site infection after orthognathic surgery in Japan.
机构信息
Department of Dentistry, Oral and Maxillofacial Plastic and Reconstructive Surgery, Faculty of Medicine, Yamagata University, Yamagata, Japan.
Division of Clinical Laboratory and Infection Control, Yamagata University Hospital, Yamagata, Japan.
出版信息
J Stomatol Oral Maxillofac Surg. 2022 Nov;123(6):e936-e939. doi: 10.1016/j.jormas.2022.06.009. Epub 2022 Jun 11.
PURPOSE
This study aimed to evaluate the risk factors for surgical site infection (SSI) after orthognathic surgery, focusing on the duration of prophylactic antibiotic administration in Japan.
STUDY DESIGN
The study included 181 patients who underwent orthognathic surgery at the Department of Oral and Maxillofacial Surgery of Yamagata University Hospital between 2012 and 2021. The clinical parameters of SSI were retrospectively investigated using patient charts. Logistic regression analysis was used to estimate the odds ratios (ORs) with 95% confidence intervals (CIs) for risk factors for SSI after orthognathic surgery.
RESULTS
Nineteen patients (10.5%) were complicated with SSI. Male sex (OR, 3.638; 95% CI, 1.316-10.058) and an antibiotic prophylaxis duration ≤3 days (OR, 12.718; 95% CI, 1.639-98.673) were independent risk factors for SSI after orthognathic surgery.
CONCLUSION
Extended-term antibiotic prophylaxis was more effective for prevention of SSI after orthognathic surgery than short-term in this study.
目的
本研究旨在评估正颌手术后手术部位感染（SSI）的风险因素，重点关注日本预防性抗生素使用时间。
研究设计
本研究纳入了 2012 年至 2021 年在山形大学医院口腔颌面外科接受正颌手术的 181 例患者。使用患者病历回顾性调查 SSI 的临床参数。使用逻辑回归分析估计正颌手术后 SSI 的风险因素的优势比（OR）及其 95%置信区间（CI）。
结果
19 例（10.5%）患者发生 SSI。男性（OR，3.638；95%CI，1.316-10.058）和抗生素预防持续时间≤3 天（OR，12.718；95%CI，1.639-98.673）是正颌手术后 SSI 的独立危险因素。
结论
在本研究中，与短期相比，长期抗生素预防更能有效预防正颌手术后 SSI。
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