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新冠疫情对重度斑秃患者的影响。

COVID-19 Pandemic Impact on Severe Alopecia Areata Patients.

作者信息

Gheisari Mehdi, Zahedi Khatere, Tehranchinia Zohreh, Moravvej Hamideh, Abdollahimajd Fahimeh, Dadkhahfar Sahar

机构信息

Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Dermatology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Skin Appendage Disord. 2022 May;8(3):195-199. doi: 10.1159/000520422. Epub 2021 Dec 20.

Abstract

INTRODUCTION

The pandemic of COVID-19 has several implications for patients with chronic stress-sensitive diseases such as alopecia areata (AA). On the other hand, the vulnerability of AA patients using immunosuppressives to a more severe infection is in the shadow of ambiguity. This teledermatology study aimed to evaluate the course and outcome of AA in patients during this challenging period.

METHODS

Patients with AA who had previously received systemic therapy included in this study. Information about demographic data, AA history, characteristics, and treatments, hair loss progression, Corona Disease Anxiety Scale (CDAS), adherence to protective measures against the COVID-19, possible infection, and its features obtained via a telephone call.

RESULTS

A total of 57 patients participated. The majority (84.2%) of the participants had mild anxiety assessed by CDAS. Two patients (3.5%) had got infected with COVID-19. Twenty-one (36.8%) participants experienced hair loss progression. Hair loss progression correlated with drug dose reduction (OR: 46.09, 95% CI 5.48-387.14, < 0.001) although it did not influence by the level of anxiety evaluated by the CDAS ( > 0.05).

CONCLUSION

The anxiety perceived by severe AA patients about COVID-19 is mild; however, many experience hair loss progressions owing to their drug dose reduction.

摘要

引言

2019年冠状病毒病(COVID-19)大流行对斑秃(AA)等慢性应激敏感疾病患者有多种影响。另一方面,使用免疫抑制剂的斑秃患者更易感染严重疾病,这一点尚不明朗。这项远程皮肤病学研究旨在评估在这一具有挑战性的时期斑秃患者的病程和结局。

方法

本研究纳入了之前接受过全身治疗的斑秃患者。通过电话获取有关人口统计学数据、斑秃病史、特征和治疗、脱发进展、冠状病毒病焦虑量表(CDAS)、针对COVID-19的防护措施依从性、可能的感染及其特征等信息。

结果

共有57名患者参与。大多数(84.2%)参与者经CDAS评估有轻度焦虑。两名患者(3.5%)感染了COVID-19。21名(36.8%)参与者出现脱发进展。脱发进展与药物剂量减少相关(比值比:46.09,95%置信区间5.48 - 387.14,P < 0.001),尽管它不受CDAS评估的焦虑水平影响(P > 0.05)。

结论

重度斑秃患者对COVID-19的焦虑较轻;然而,许多患者因药物剂量减少而出现脱发进展。

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