Department of Anesthesia, Bethune First Hospital of Jilin University, Changchun, Jilin130000, China.
Department of Radiology, Bethune First Hospital of Jilin University, Changchun, Jilin 130000, China.
Geriatr Nurs. 2022 Jul-Aug;46:144-156. doi: 10.1016/j.gerinurse.2022.05.010. Epub 2022 Jun 11.
Perioperative neurocognitive dysfunction comprises pre-existing neurocognitive dysfunction, postoperative delirium (POD), and postoperative cognitive dysfunction (POCD). This meta-analysis aims to study the effects of transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive function after general anesthesia in older adults. Eight databases were searched, from the establishment of the databases to January 2022. Eighteen randomized controlled trials were included. TEAS reduced POCD incidence on the 1st and 3rd but not on the 5th and 7th postoperative days (p<0.00001; p<0.00001; p = 0.20; p = 0.30). Owing to the limited number of original studies, POD incidence could not be analyzed. TEAS improved the MMSE scores on the 1st and 3rd but not on the 5th and 7th postoperative days. TEAS reduced the values of S100β at the end of the surgery and 1 day after surgery and IL-6 on the 1st postoperative day. TEAS can prevent early postoperative cognitive decline after general anesthesia in older adults.
围手术期神经认知功能障碍包括术前神经认知功能障碍、术后谵妄（POD）和术后认知功能障碍（POCD）。本荟萃分析旨在研究经皮穴位电刺激（TEAS）对老年全麻术后认知功能的影响。从数据库建立到 2022 年 1 月，检索了 8 个数据库。共纳入 18 项随机对照试验。TEAS 降低了术后第 1 天和第 3 天 POCD 的发生率，但对第 5 天和第 7 天无影响（p<0.00001;p<0.00001;p=0.20;p=0.30）。由于原始研究数量有限，无法分析 POD 的发生率。TEAS 可改善术后第 1 天和第 3 天的 MMSE 评分，但对第 5 天和第 7 天无影响。TEAS 可降低手术结束时和术后第 1 天 S100β 值以及术后第 1 天 IL-6 值。TEAS 可预防老年全麻术后早期认知功能下降。
