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2015年哥伦比亚北部种族与高血压之间的关联。

Association between ethnicity and hypertension in Northern Colombia in 2015.

作者信息

Smith Drew H, Grewal Jaskaran, Mehboob Saba, Mohan Shiva, Pombo Luisa F, Rodriguez Pura, Gonzalez Juan Carlos, Zevallos Juan, Barengo Noël C

机构信息

Department of Translational Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.

Florida International University Herbert Wertheim College of Medicine, 11200 SW 8th Street, 33199, Miami, FL, USA.

出版信息

Clin Hypertens. 2022 Jun 15;28(1):18. doi: 10.1186/s40885-022-00203-8.

Abstract

BACKGROUND

Studies in the United States have shown a genetic predisposition to hypertension in individuals of African descent. However, studies on the associations between ethnic groups and hypertension in Latin America are lacking and the limited results have been inconsistent. The objective of this study is to determine whether Afro-Colombian ethnicity increases the risk of hypertension.

METHODS

This study is a secondary data analysis of a cross sectional study from five provinces in Northern Colombia. Randomly selected individuals (N = 2613; age-range 18-74 years) enrolled in a health care insurance company underwent physical examinations and completed questionnaires regarding ethnicity, lifestyle, and other risk factors. Hypertension in these patients was determined. Unadjusted and adjusted logistic regression analysis were calculated to determine the association between ethnicity and hypertension.

RESULTS

No association between Afro-Colombian ethnicity and hypertension was found (odds ratio [OR], 0.85; 95% confidence interval [CI], 0.66-1.09). As expected, people with a body mass index (BMI) of 30 or higher were at a greater risk of having hypertension (OR, 3.12; 95% CI, 2.35-4.16) compared with those with a normal BMI.

CONCLUSIONS

Findings from this study suggest no independent association between Afro-Colombian ethnicity and hypertension. Further research should focus on genotyping or socioeconomic factors such as income level.

摘要

背景

美国的研究表明,非洲裔个体存在高血压的遗传易感性。然而,拉丁美洲关于种族群体与高血压之间关联的研究较少,且有限的研究结果并不一致。本研究的目的是确定非裔哥伦比亚人种族是否会增加患高血压的风险。

方法

本研究是对哥伦比亚北部五个省份的一项横断面研究的二次数据分析。随机选取了加入一家医疗保险公司的个体(N = 2613;年龄范围18 - 74岁)进行体格检查,并完成了关于种族、生活方式和其他风险因素的问卷调查。确定了这些患者的高血压情况。计算未调整和调整后的逻辑回归分析,以确定种族与高血压之间的关联。

结果

未发现非裔哥伦比亚人种族与高血压之间存在关联(优势比[OR],0.85;95%置信区间[CI],0.66 - 1.09)。正如预期的那样,与体重指数(BMI)正常的人相比,BMI为30或更高的人患高血压的风险更大(OR,3.12;95% CI,2.35 - 4.16)。

结论

本研究结果表明,非裔哥伦比亚人种族与高血压之间不存在独立关联。进一步的研究应侧重于基因分型或社会经济因素,如收入水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/114b/9199244/c0ac4b6f7021/40885_2022_203_Fig1_HTML.jpg

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