Navarro Anne-Sophie, Angeles Martina Aida, Illac Claire, Boulet Bérénice, Ferron Gwenael, Martinez Alejandra
Department of Surgical Oncology, Institut Claudius Regaud-Institut Universitaire du Cancer de Toulouse (IUCT), Oncopole, Toulouse, France.
Department of Pathology, Institut Claudius Regaud-Institut Universitaire du Cancer de Toulouse (IUCT), Oncopole, Toulouse, France.
J Surg Case Rep. 2022 Jun 10;2022(6):rjac166. doi: 10.1093/jscr/rjac166. eCollection 2022 Jun.
Disseminated peritoneal leiomyomatosis (DPL) is a rare gynecologic disease involving multifocal proliferation of myomas. The pathogenesis remains unclear. Although there is no standard treatment, medical therapies have attempted to suppress estrogen levels by using gonadotrophin-releasing hormone agonist and aromatase inhibitor (AI) therapy with differing degrees of success. Surgery is also an option in symptomatic patients, and in the event of partial or no response to medical treatments. We report a case of DPL in a young woman with a previous history of myomectomy. She was treated sequentially with ulipristal acetate and AI.
播散性腹膜平滑肌瘤病（DPL）是一种罕见的妇科疾病，涉及肌瘤的多灶性增殖。其发病机制尚不清楚。虽然没有标准治疗方法，但医学治疗已尝试通过使用促性腺激素释放激素激动剂和芳香化酶抑制剂（AI）来抑制雌激素水平，取得了不同程度的成功。对于有症状的患者以及对药物治疗部分或无反应的情况，手术也是一种选择。我们报告一例有子宫肌瘤切除术史的年轻女性的DPL病例。她先后接受了醋酸乌利司他和AI治疗。
