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花粉季节内外鼻黏膜肥大细胞数量的变化。

Changes in nasal mast cell numbers in and out of the pollen season.

作者信息

Viegas M, Gomez E, Brooks J, Davies R J

出版信息

Int Arch Allergy Appl Immunol. 1987;82(3-4):275-6. doi: 10.1159/000234205.

DOI:10.1159/000234205
PMID:3570499
Abstract

Mast cells were counted in biopsies of the nasal mucous membrane from 8 patients with allergic rhinitis during (July 1985) and after (October 1985 and January 1986) the grass pollen season in both the superficial epithelium and the deeper lamina propria. There was an eightfold increase in the total number of mast cells in the nasal mucous membrane during the grass pollen season when compared to midwinter. In addition, there was a striking change in the number of mast cells present in the surface epithelial layer from almost total absence in biopsies taken in midwinter to counts of between 2,000 and 28,000/mm3 in all but 1 patient during the summer.

摘要

对8例变应性鼻炎患者在草花粉季节期间(1985年7月)及之后(1985年10月和1986年1月)的鼻黏膜活检组织进行肥大细胞计数,计数部位包括浅表上皮和更深层的固有层。与冬季中期相比,草花粉季节期间鼻黏膜中肥大细胞总数增加了8倍。此外,表面上皮层中肥大细胞数量发生了显著变化,从冬季中期活检组织中几乎完全不存在,到夏季除1例患者外所有患者的计数在2000至28000个/mm³之间。

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