支架辅助弹簧圈治疗后发生超急性支架内血栓形成导致大血管闭塞：氯吡格雷和普拉格雷完全抵抗一例报告。
Hyperacute in-Stent Thrombosis Causing Large Vessel Occlusion after Stent-Assisted Aneurysm Coiling Secondary to Complete Clopidogrel and Prasugrel Resistance: a Case Report.
机构信息
Royal Prince Alfred Hospital, Camperdown, NSW, Sydney, Australia.
出版信息
J Neurol Surg A Cent Eur Neurosurg. 2024 Sep;85(5):531-533. doi: 10.1055/a-1877-0421. Epub 2022 Jun 15.
PMID:35705178
Abstract
Dual antiplatelet therapy (DAPT) is standard treatment for endoluminal stent insertion, and complete resistance to DAPT is rare. A case of in-stent thrombosis occurring 3 hours after stent-assisted coiling of internal carotid artery aneurysm is presented despite compliance with DAPT. Platelet function tests (PFTs) revealed complete clopidogrel and prasugrel resistance.
摘要
双联抗血小板治疗（DAPT）是腔内支架置入的标准治疗方法，完全抵抗 DAPT 的情况很少见。尽管遵守了 DAPT，但在支架辅助弹簧圈栓塞颈内动脉动脉瘤后 3 小时仍发生支架内血栓形成。血小板功能检测（PFT）显示氯吡格雷和普拉格雷完全抵抗。
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