Department of Computer Science, Aalto University, 00076 Espoo, Finland.
Phys Rev E. 2022 May;105(5):L052301. doi: 10.1103/PhysRevE.105.L052301.
We study how the herd immunity threshold and the expected epidemic size depend on homophily with respect to vaccine adoption. We find that the presence of homophily considerably increases the critical vaccine coverage needed for herd immunity and that strong homophily can push the threshold entirely out of reach. The epidemic size monotonically increases as a function of homophily strength for a perfect vaccine, while it is maximized at a nontrivial level of homophily when the vaccine efficacy is limited. Our results highlight the importance of vaccination homophily in epidemic modeling.
我们研究了群体免疫阈值和预期疫情规模如何取决于疫苗接种的同质性。我们发现,同质性的存在大大增加了群体免疫所需的关键疫苗接种覆盖率,而且强烈的同质性可能会使阈值完全无法达到。对于完美疫苗,疫情规模随着同质性强度单调增加,而当疫苗效力有限时,疫情规模在非平凡的同质性水平上达到最大化。我们的研究结果强调了在传染病建模中疫苗接种同质性的重要性。