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本文引用的文献

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Comparison of 2-Chloroprocaine, Bupivacaine, and Lidocaine for Spinal Anesthesia in Patients Undergoing Knee Arthroscopy in an Outpatient Setting: A Double-Blind Randomized Controlled Trial.门诊膝关节镜检查患者中2-氯普鲁卡因、布比卡因和利多卡因用于脊髓麻醉的比较:一项双盲随机对照试验
Reg Anesth Pain Med. 2016 Sep-Oct;41(5):576-83. doi: 10.1097/AAP.0000000000000420.
2
Spinal 1% 2-Chloroprocaine versus general anesthesia for ultra-short outpatient procedures: a retrospective analysis.用于超短门诊手术的脊髓注射1% 2-氯普鲁卡因与全身麻醉的回顾性分析。
Acta Biomed. 2014 Dec 17;85(3):265-8.
3
Short-acting spinal anesthesia in the ambulatory setting.门诊环境下的短效脊髓麻醉。
Curr Opin Anaesthesiol. 2014 Dec;27(6):597-604. doi: 10.1097/ACO.0000000000000126.
4
Intrathecal 1% 2-chloroprocaine vs. 0.5% bupivacaine in ambulatory surgery: a prospective, observer-blinded, randomised, controlled trial.门诊手术中鞘内注射1%氯普鲁卡因与0.5%布比卡因的比较:一项前瞻性、观察者盲法、随机对照试验。
Acta Anaesthesiol Scand. 2014 May;58(5):560-6. doi: 10.1111/aas.12291. Epub 2014 Mar 6.
5
Intrathecal chloroprocaine vs. lidocaine in day-case surgery: recovery, discharge and effect of pre-hydration on micturition.日间手术中鞘内注射氯普鲁卡因与利多卡因的比较:恢复情况、出院情况及术前补液对排尿的影响
Acta Anaesthesiol Scand. 2014 Feb;58(2):206-13. doi: 10.1111/aas.12247.
6
Assessment of block height for satisfactory spinal anaesthesia for caesarean section.评估剖宫产术满意的脊髓麻醉阻滞平面。
Anaesthesia. 2012 Dec;67(12):1356-63. doi: 10.1111/anae.12034. Epub 2012 Oct 12.
7
Chloroprocaine for spinal anesthesia: a retrospective analysis.氯普鲁卡因用于椎管内麻醉:回顾性分析。
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8
Spinal anesthesia with lidocaine or preservative-free 2-chlorprocaine for outpatient knee arthroscopy: a prospective, randomized, double-blind comparison.利多卡因或无防腐剂的2-氯普鲁卡因用于门诊膝关节镜检查的脊髓麻醉:一项前瞻性、随机、双盲比较研究。
Anesth Analg. 2007 Apr;104(4):959-64. doi: 10.1213/01.ane.0000258766.73612.d8.
9
A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials.门诊麻醉中区域麻醉与全身麻醉的比较:一项随机对照试验的荟萃分析。
Anesth Analg. 2005 Dec;101(6):1634-1642. doi: 10.1213/01.ANE.0000180829.70036.4F.
10
Spinal 2-chloroprocaine: a comparison with small-dose bupivacaine in volunteers.脊髓用2-氯普鲁卡因:与小剂量布比卡因在志愿者中的比较。
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等比重氯普鲁卡因脊髓麻醉与全身麻醉用于短期门诊泌尿外科手术的比较。

Comparison of spinal anaesthesia with isobaric chloroprocaine and general anaesthesia for short duration ambulatory urological procedures.

作者信息

Ravi Siddarth, Krishna Handattu M

机构信息

Department of Anesthesiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2022 Jan-Mar;38(1):91-96. doi: 10.4103/joacp.JOACP_131_20. Epub 2022 Feb 10.

DOI:10.4103/joacp.JOACP_131_20
PMID:35706653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9191783/
Abstract

BACKGROUND AND AIMS

Chloroprocaine is a short-acting local anaesthetic agent for spinal anaesthesia (SA) that has been used in day care surgeries due to its faster recovery characteristics and faster discharge rates compared to other local anaesthetics. This study aimed at finding out its efficacy for the same as compared to general anaesthesia (GA).

MATERIAL AND METHODS

This observational study was conducted on 60 patients belonging to the American Society of Anaesthesiologists (ASA) physical status I and II who underwent short elective urological procedures (<60 min) under GA (group GA) as per standard of care in our hospital (n = 30) and SA (group SA) with 50 mg 1% isobaric 2-Chloroprocaine (n = 30). Time taken to meet the discharge criteria, modified Aldrete score and modified post anaesthesia discharge score in each group were noted. The cost of the anaesthetic procedure, anaesthetic procedural time, hemodynamics, supplemental analgesia, complications related to the procedure were noted and compared.

RESULTS

Patient characteristics and duration of surgery were comparable. Time taken by group SA was significantly higher than group GA to meet the discharge criteria. Cost of GA [2624.76 (166.16) units] was significantly more than SA [1561.63 (81.32) units, < 0.05]. There was no requirement of supplemental analgesia in group SA and no hemodynamic instability or complications in either group.

CONCLUSION

GA is significantly better as compared to SA with 50 mg 1% isobaric 2-Chloroprocaine as an anesthetic technique in day care urology surgeries in terms of faster recovery and faster discharge rate but is costlier.

摘要

背景与目的

氯普鲁卡因是一种用于脊髓麻醉(SA)的短效局部麻醉剂,由于其与其他局部麻醉剂相比具有更快的恢复特性和更快的出院率,已被用于日间手术。本研究旨在找出其与全身麻醉(GA)相比在这方面的疗效。

材料与方法

本观察性研究对60例美国麻醉医师协会(ASA)身体状况为I级和II级的患者进行,这些患者在我院按照标准护理流程接受了短时间择期泌尿外科手术(<60分钟),其中30例接受全身麻醉(GA组),30例接受脊髓麻醉(SA组),SA组使用50毫克1%等比重2 - 氯普鲁卡因。记录每组达到出院标准所需时间、改良Aldrete评分和改良麻醉后出院评分。记录并比较麻醉过程的费用、麻醉操作时间、血流动力学、补充镇痛情况以及与手术相关的并发症。

结果

患者特征和手术持续时间具有可比性。SA组达到出院标准所需时间显著长于GA组。GA的费用[2624.76(166.16)单位]显著高于SA组[1561.63(81.32)单位,P<0.05]。SA组无需补充镇痛,两组均未出现血流动力学不稳定或并发症。

结论

在日间泌尿外科手术中,作为一种麻醉技术,与使用50毫克1%等比重2 - 氯普鲁卡因的脊髓麻醉相比,全身麻醉在恢复更快和出院率更快方面显著更好,但费用更高。