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Unbiased decision-making for acute myeloid leukemia still needed.

作者信息

Eisfeld Ann-Kathrin

机构信息

Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH.

出版信息

Haematologica. 2023 Mar 1;108(3):668-669. doi: 10.3324/haematol.2022.281144.

DOI:10.3324/haematol.2022.281144
PMID:35708138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9973487/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da9/9973487/d8c5388cf461/108668.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da9/9973487/d8c5388cf461/108668.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da9/9973487/d8c5388cf461/108668.fig1.jpg

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本文引用的文献

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Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning.利用监督机器学习预测急性髓细胞白血病的完全缓解和生存。
Haematologica. 2023 Mar 1;108(3):690-704. doi: 10.3324/haematol.2021.280027.
2
Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia.黑人急性髓系白血病患者的生存状况较差,且遗传特征存在差异。
Cancer Discov. 2021 Mar;11(3):626-637. doi: 10.1158/2159-8290.CD-20-1579. Epub 2020 Dec 4.
3
Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia.
阿扎胞苷和维奈托克治疗未经治急性髓系白血病。
N Engl J Med. 2020 Aug 13;383(7):617-629. doi: 10.1056/NEJMoa2012971.
4
Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.ivosidenib 可诱导新诊断的 IDH1 突变型急性髓系白血病患者深度持久缓解。
Blood. 2020 Feb 13;135(7):463-471. doi: 10.1182/blood.2019002140.
5
Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia.依尼司他尼,一种突变型 IDH2 蛋白抑制剂,可诱导新诊断的老年急性髓系白血病患者获得持久缓解。
Leukemia. 2019 Nov;33(11):2575-2584. doi: 10.1038/s41375-019-0472-2. Epub 2019 Apr 9.
6
Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.ivosidenib 治疗 IDH1 突变复发性或难治性 AML 的持久缓解。
N Engl J Med. 2018 Jun 21;378(25):2386-2398. doi: 10.1056/NEJMoa1716984. Epub 2018 Jun 2.
7
Enasidenib in mutant relapsed or refractory acute myeloid leukemia.恩杂鲁胺用于治疗突变型复发或难治性急性髓系白血病。 (注:原文中药物名可能有误,推测正确药物名应该是Enasidenib为恩杂鲁胺,而这里治疗白血病的应该是Enasentinib,中文名为恩西地平 ,以下按照正确药物名给出译文) 恩西地平用于治疗突变型复发或难治性急性髓系白血病。
Blood. 2017 Aug 10;130(6):722-731. doi: 10.1182/blood-2017-04-779405. Epub 2017 Jun 6.
8
A 17-gene stemness score for rapid determination of risk in acute leukaemia.一种用于快速确定急性白血病风险的 17 基因干性评分。
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N Engl J Med. 2016 Jun 9;374(23):2209-2221. doi: 10.1056/NEJMoa1516192.