Rand J S, O'Brien P J
J Am Vet Med Assoc. 1987 Apr 15;190(8):1013-4.
An exercise-induced malignant hyperthermia-like syndrome developed in an English Springer Spaniel. Moderate exercise resulted in pronounced hyperlactacidemia, dyspnea, and hyperthermia. Before exercise, the dog had high activities of serum muscle enzymes, mild reticulocytosis, abnormally increased erythrocyte osmotic fragility, and a positive result from the caffeine-halothane contracture test. This report supports the hypothesis of a canine stress syndrome and indicates a role for exercise/challenge tests in diagnosis of malignant hyperthermia susceptibility.
一只英国激飞猎犬出现了运动诱发的恶性高热样综合征。适度运动导致明显的高乳酸血症、呼吸困难和体温过高。运动前，该犬血清肌肉酶活性高、轻度网织红细胞增多、红细胞渗透脆性异常增加，咖啡因-氟烷挛缩试验结果呈阳性。本报告支持犬应激综合征的假说，并表明运动/激发试验在恶性高热易感性诊断中的作用。
