Enzymatic phosphorylation of macrolide antibiotics.
作者信息
Wiley P F, Baczynskyj L, Dolak L A, Cialdella J I, Marshall V P
出版信息
J Antibiot (Tokyo). 1987 Feb;40(2):195-201. doi: 10.7164/antibiotics.40.195.
PMID:3570968
Abstract
Five macrolide antibiotics (erythromycin A, 1; oleandomycin, 3a; tylosin, 4a; spiramycins, 5a; leucomycin A3, 6a) have been phosphorylated enzymatically using cell-free extracts derived from Streptomyces coelicolor UC 5240. The necessary cofactors and the rates of the conversion have been determined.
摘要
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