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本文引用的文献

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Inactivation of rifampin by Nocardia brasiliensis.巴西诺卡菌对利福平的灭活作用。
Antimicrob Agents Chemother. 1993 Jun;37(6):1313-7. doi: 10.1128/AAC.37.6.1313.
2
Inactivated products of rifampicin by pathogenic Nocardia spp.: structures of glycosylated and phosphorylated metabolites of rifampicin and 3-formylrifamycin SV.
J Antibiot (Tokyo). 1993 Oct;46(10):1605-10. doi: 10.7164/antibiotics.46.1605.
3
Microbial conversion of avermectins by Saccharopolyspora erythraea: glycosylation at C-4' and C-4''.糖多孢红霉菌对阿维菌素的微生物转化：C-4'和C-4''位的糖基化
Antimicrob Agents Chemother. 1993 Sep;37(9):1737-41. doi: 10.1128/AAC.37.9.1737.
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Studies on antibiotic SF-837, a new antibiotic. IV. Structures of antibiotics SF-837 A 2 , A 3 and A 4 .新型抗生素SF - 837的研究。IV. 抗生素SF - 837 A2、A3和A4的结构。
J Antibiot (Tokyo). 1971 Aug;24(8):526-36. doi: 10.7164/antibiotics.24.526.
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Enzymatic phosphorylation of macrolide antibiotics.
J Antibiot (Tokyo). 1987 Feb;40(2):195-201. doi: 10.7164/antibiotics.40.195.
6
Particular utility of the HMBC technique to polypropionate derived metabolites as exemplified by erythromycin A.HMBC技术对聚丙酸酯衍生代谢物的特殊效用，以红霉素A为例。
J Antibiot (Tokyo). 1988 Aug;41(8):1158-60. doi: 10.7164/antibiotics.41.1158.
7
Microbial O-phosphorylation of macrolide antibiotics.
J Antibiot (Tokyo). 1989 Jan;42(1):132-4. doi: 10.7164/antibiotics.42.132.
8
In vitro susceptibility of Nocardia spp. to a new fluoroquinolone, tosufloxacin (T-3262).诺卡氏菌属对新型氟喹诺酮类药物妥舒沙星（T-3262）的体外敏感性
Antimicrob Agents Chemother. 1989 Dec;33(12):2140-1. doi: 10.1128/AAC.33.12.2140.
9
Microbial glycosylation of erythromycin A.红霉素A的微生物糖基化作用。
Antimicrob Agents Chemother. 1989 Dec;33(12):2089-91. doi: 10.1128/AAC.33.12.2089.
10
Purification and characterization of macrolide 2'-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin.从一株对红霉素高度耐药的大肠杆菌中纯化和鉴定大环内酯2'-磷酸转移酶
Antimicrob Agents Chemother. 1989 Aug;33(8):1354-7. doi: 10.1128/AAC.33.8.1354.

致病性诺卡氏菌属对大环内酯类抗生素红霉素、麦迪霉素和罗他霉素的灭活作用

Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species.

作者信息

Yazawa K, Mikami Y, Sakamoto T, Ueno Y, Morisaki N, Iwasaki S, Furihata K

机构信息

Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.

出版信息

Antimicrob Agents Chemother. 1994 Sep;38(9):2197-9. doi: 10.1128/AAC.38.9.2197.

DOI:10.1128/AAC.38.9.2197
PMID:7811046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC284711/
Abstract

A survey of five Nocardia spp. with respect to susceptibility towards three macrolides (erythromycin, rokitamycin, and midecamycin) showed that the Nocardia spp. have different susceptibility profiles. Most of the resistance was due to the inactivation of the macrolides by phosphorylation, glycosylation, reduction, deacylation, or a combination thereof.

摘要

一项针对五种诺卡氏菌属细菌对三种大环内酯类抗生素（红霉素、罗他霉素和麦迪霉素）敏感性的调查显示，这些诺卡氏菌属细菌具有不同的敏感性特征。大多数耐药性是由于大环内酯类抗生素通过磷酸化、糖基化、还原、脱酰化或这些作用的组合而失活。