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尼日利亚私营部门疟疾快速诊断检测市场:2018 年市场调查结果。

The private sector market for malaria rapid diagnostic tests in Nigeria: results of the 2018 market survey.

机构信息

Malaria Consortium Headquarters, 244-254 Cambridge Heath Rd, London, E2 9DA, UK.

Innovision Consulting Private Limited, Level 3 & 4 House 26 Road 6 Baridhara J Block Pragati Sarani, Dhaka, 1212, Bangladesh.

出版信息

Malar J. 2022 Jun 16;21(1):190. doi: 10.1186/s12936-022-04209-3.

Abstract

BACKGROUND

To avoid misuse of anti-malarials, correct diagnosis of fever prior to drug prescription is essential. Presumptive treatment in the private healthcare sector is a concern in Nigeria, where availability of affordable artemisinin-based combination therapy (ACT) is high following the implementation of subsidy schemes from 2010 to 2017. Similar subsidies have not, however, been implemented for malaria rapid diagnostic tests (RDTs). A market survey in 2018 predominantly designed to assess the ACT market in the private sector also collected data related to RDTs, results of which are presented herein.

METHODS

A 2018 market survey consisted of (i) an outlet survey targeting private pharmacies and Proprietary and Patent Medicine Vendors (PPMVs) across different regions of Nigeria to assess supply-side market factors related to availability of RDTs (defined as having stock available for purchase at the time of the survey) and (ii) a household survey to determine demand-side factors related to knowledge of RDTs, healthcare-seeking practices and affordability.

RESULTS

Availability of RDTs at the time of the survey was low in both outlet types and significantly lower in PPMVs (22.1%, 95% CI) among pharmacies versus (13.6%, 95% CI) among PPMVs (p < 0.01). Reasons for not restocking RDTs included low demand and no supply. The majority of households diagnose malaria based on experience, while one-third would visit a PPMV or pharmacy. Half of households had heard of RDTs (48.4%) and 38.6% thought they were affordable.

CONCLUSIONS

Low availability of RDTs among PPMVs and pharmacies may be attributed to lack of demand, supply-side issues and cost. Increasing household knowledge of RDTs may aid increasing demand, while subsidized RDTs may address supply and price issues. Addressing the deficit in RDT provision is important for targeting of ACT medicines.

摘要

背景

为避免抗疟药物的滥用,在开具药物之前正确诊断发热至关重要。在尼日利亚,私营医疗部门存在经验性治疗的问题,令人担忧,因为自 2010 年至 2017 年实施补贴计划后,青蒿素为基础的联合治疗药物(ACT)的供应变得负担得起。然而,类似的补贴并没有用于疟疾快速诊断检测(RDT)。2018 年进行的一项市场调查主要旨在评估私营部门的 ACT 市场,也收集了与 RDT 相关的数据,现将结果报告如下。

方法

2018 年的市场调查包括:(i)一项针对私营药店和专利药品供应商(PPMV)的出口调查,评估 RDT 供应方面的市场因素(定义为在调查时库存可用于购买);(ii)一项家庭调查,以确定与 RDT 知识、卫生保健寻求行为和负担能力相关的需求方面的因素。

结果

在调查时,两种类型的出口处 RDT 的供应都很低,PPMV 中的 RDT 供应明显更低(22.1%,95%置信区间),而在 PPMV 中的 RDT 供应更低(13.6%,95%置信区间)(p<0.01)。不补充 RDT 的原因包括需求低和无供应。大多数家庭根据经验诊断疟疾,而三分之一的家庭会去 PPMV 或药店就诊。一半的家庭听说过 RDT(48.4%),而 38.6%的家庭认为它们负担得起。

结论

PPMV 和药店中 RDT 的供应不足可能归因于需求低、供应方面的问题和价格。增加家庭对 RDT 的了解可能有助于增加需求,而补贴 RDT 可能解决供应和价格问题。解决 RDT 供应不足的问题对于 ACT 药物的目标定位非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f0a/9205121/749ea4bab52e/12936_2022_4209_Fig1_HTML.jpg

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