Perna Simone, Salman Majeda, Gasparri Clara, Cavioni Alessandro, Faliva Milena Anna, Mansueto Francesca, Naso Maurizio, Patelli Zaira, Peroni Gabriella, Tartara Alice, Riva Antonella, Petrangolini Giovanna, Rondanelli Mariangela
Department of Biology, College of Science, University of Bahrain, Sakhir, Bahrain.
Department of Mathematics, College of Science, University of Bahrain, Sakhir, Bahrain.
Front Nutr. 2022 May 27;9:851802. doi: 10.3389/fnut.2022.851802. eCollection 2022.
The aim of the present study was to assess the dropout rate at 2, 6, and 12 months after an inpatient multidisciplinary residential program (MRP) for the treatment of obesity. Furthermore, this study assessed anthropometric and biochemical predictors associated with the dropout.
Adult and elderly patients (age 59 ± 14 years) with obesity had undergone an MRP, were followed up from 2 to 12 months. Biochemical and anthropometric markers have been assessed at the beginning of the follow-up period after the MRP.
The study enrolled 178 subjects, 117 women and 61 men. The overall dropout rate at 2 months was 21.3%, after 6 months was 44.4%, and after 1 year was 68.5%. There was no difference by gender recorded. Furthermore, patients under medical treatment with psychiatric disorders did not show an association with the dropout rate. Patients with a higher level of body mass index (BMI) at the discharge of MRP showed +48% of dropout at 6 months. After the MRP, the baseline values of uricemia and white blood cells (WBCs) resulted as predictors of dropout at 2 months ( > 0.05). Furthermore, the excess percentage of fat mass lost during the MRP was associated with the risk of dropout at 2, 6, and 12 months ( > 0.05).
The MRP for obesity is an opportunity for losing weight for patients with established criteria. The future challenge will be addressing the best strategic plans in order to reduce the dropout rate after this intervention. Investigating deeply the main predictors could be an opportunity to improve the long-term efficacy of MRP.
本研究旨在评估住院多学科住院治疗项目(MRP)治疗肥胖症后2个月、6个月和12个月时的退出率。此外,本研究还评估了与退出相关的人体测量和生化预测因素。
患有肥胖症的成年和老年患者(年龄59±14岁)接受了MRP治疗,并进行了2至12个月的随访。在MRP后的随访期开始时评估了生化和人体测量指标。
该研究招募了178名受试者,其中117名女性和61名男性。2个月时的总体退出率为21.3%,6个月后为44.4%,1年后为68.5%。未记录到性别差异。此外,接受精神疾病治疗的患者与退出率无关。MRP出院时体重指数(BMI)较高的患者在6个月时的退出率增加了48%。MRP后,血尿酸和白细胞(WBC)的基线值是2个月时退出的预测因素(>0.05)。此外,MRP期间脂肪量减少的多余百分比与2个月、6个月和12个月时的退出风险相关(>0.05)。
肥胖症的MRP为符合既定标准的患者提供了减肥的机会。未来的挑战将是制定最佳战略计划,以降低这种干预后的退出率。深入研究主要预测因素可能是提高MRP长期疗效的一个机会。