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增强型认知行为疗法治疗进食障碍的疗效:一项随机对照试验。

Effectiveness of enhanced cognitive behavior therapy for eating disorders: A randomized controlled trial.

机构信息

Center for Eating Disorders, PsyQ, Part of Parnassia Psychiatric Institute, The Hague, The Netherlands.

Parnassia Psychiatric Institute, The Hague, The Netherlands.

出版信息

Int J Eat Disord. 2020 May;53(5):447-457. doi: 10.1002/eat.23239. Epub 2020 Feb 10.

Abstract

OBJECTIVE

Enhanced cognitive behavior therapy (CBT-E) is a transdiagnostic treatment suitable for the full range of eating disorders (EDs). Although the effectiveness of CBT(-E) is clear, it is not being used as widely in clinical practice as guidelines recommend. The aim of the present study was to compare the effectiveness of CBT-E with treatment as usual (TAU), which was largely based on CBT principles.

METHOD

We conducted a randomized controlled trial on a total of 143 adult patients with an ED who received either CBT-E or TAU. The primary outcome was recovery from the ED. Secondary outcome measures were levels of ED psychopathology, anxiety, and depressive symptoms. Self-esteem, perfectionism, and interpersonal problems were repeatedly measured to examine possible moderating effects. We explored differences in duration and intensity between conditions.

RESULTS

After 80 weeks, there were no differences between conditions in decrease in ED psychopathology, or symptoms of anxiety and depression. However, in the first six weeks of treatment there was a larger decrease in ED psychopathology in the CBT-E condition. Moreover, when the internationally most widely used definition of recovery was applied, the recovery rate at 20 weeks of CBT-E was significantly higher (57.7%) than of TAU (36.0%). At 80 weeks, this difference was no longer significant (CBT-E 60.9%; TAU 43.6%). Furthermore, CBT-E was more effective in improving self-esteem and was also the less intensive and shorter treatment.

DISCUSSION

With broader use of CBT-E, the efficiency, accessibility and effectivity (on self-esteem) of treatment for EDs could be improved.

摘要

目的

强化认知行为疗法(CBT-E)是一种适用于各种饮食障碍(ED)的跨诊断治疗方法。尽管 CBT-E 的有效性已得到明确证实,但它在临床实践中的应用并未像指南所建议的那样广泛。本研究旨在比较 CBT-E 与主要基于 CBT 原则的常规治疗(TAU)的疗效。

方法

我们对共 143 名患有 ED 的成年患者进行了一项随机对照试验,这些患者分别接受 CBT-E 或 TAU 治疗。主要结局是 ED 的康复。次要结局指标为 ED 心理病理学、焦虑和抑郁症状的水平。自尊、完美主义和人际关系问题被反复测量,以检验可能的调节作用。我们探讨了条件之间在持续时间和强度上的差异。

结果

在 80 周后,两种条件在 ED 心理病理学或焦虑和抑郁症状的减少方面没有差异。然而,在治疗的前六周,CBT-E 组的 ED 心理病理学减少幅度更大。此外,当采用国际上最广泛使用的康复定义时,CBT-E 的康复率在 20 周时显著高于 TAU(57.7%比 36.0%)。在 80 周时,这种差异不再显著(CBT-E 为 60.9%;TAU 为 43.6%)。此外,CBT-E 更有效地改善了自尊,且治疗的强度和持续时间也更短。

讨论

更广泛地使用 CBT-E 可以提高 ED 治疗的效率、可及性和有效性(在自尊方面)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9255/7317943/ad23014a1a10/EAT-53-717-g001.jpg

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