University of Puthisastra, Phnom Penh, Cambodia.
Henry M. Goldman School of Dental Medicine, Boston University, Boston, Massachusetts, USA.
J Glob Health. 2022 Jun 18;12:04046. doi: 10.7189/jogh.12.04046.
The evidence around the relationship between Early Childhood Caries (ECC) and undernutrition is sparse and mostly reported from cross-sectional data sets. This paper aimed to test the relationship between ECC and linear and ponderal growth trajectories.
This project involves secondary data analysis from the Cambodia Longitudinal Health and Nutrition Study. The analytical sample included a 2y-cohort of 894 children who were younger than 2 years of age at the time of first height and weight measurement. Statistical analysis used both logistic regression modelling and Latent Class Analysis to examine the effect of exposure to dental caries in the first 1000 days on weight for height Z-score (WHZ) and height for age Z-score (HAZ) trajectory class groups. The presence of any cavity and pulp involvement were examined using multinomial regression adjusting for gender, socioeconomic status, maternal age and education.
Within each class groupings (HAZ and WHZ groupings), there was a trend whereby those with one or more cavities had lower Z-scores across the three follow-up time points of observation. There was an association between exposure to caries and WHZ class membership whereby children with caries exposure were more likely belong to WHZ class groups with lower Z-scores over time.
The study offers evidence that ECC is correlated with less favourable ponderal growth categorized by WHZ trajectory class groups.
有关婴幼儿龋（ECC）和营养不良之间关系的证据很少，并且主要来自横断面数据集。本文旨在检验 ECC 与线性和体积生长轨迹之间的关系。
本项目涉及柬埔寨纵向健康和营养研究的二次数据分析。分析样本包括一个 2 岁以下的 894 名儿童队列，他们在首次进行身高和体重测量时年龄不到 2 岁。统计分析使用逻辑回归模型和潜在类别分析来检验暴露于生命最初 1000 天内龋齿对身高体重 Z 分数（WHZ）和身高年龄 Z 分数（HAZ）轨迹类别组的影响。使用多元回归调整性别、社会经济地位、母亲年龄和教育水平，检查任何龋齿和牙髓受累的情况。
在每个分组（HAZ 和 WHZ 分组）中，有一种趋势是，有一个或多个龋齿的儿童在三个随访观察时间点的 Z 分数较低。龋齿暴露与 WHZ 类别成员之间存在关联，暴露于龋齿的儿童更有可能随着时间的推移属于 WHZ 类别组，其 Z 分数较低。
该研究提供了证据表明，ECC 与通过 WHZ 轨迹类别组分类的不良体脂生长有关。
