Pakistan Naval Hospital, PNS Hafeez, Naval Complex, Islamabad, Pakistan.
Department of Environmental Design Health and Nutritional Sciences, Allama Iqbal Open University, Islamabad, Pakistan.
J Pak Med Assoc. 2022 May;72(5):860-865. doi: 10.47391/JPMA.1890.
To assess the pre-operative nutritional status and its effect on wound healing of patients having undergone coronary artery bypass graft surgery.
The hospital-based prospective study was conducted at the Armed Forces Institute of Cardiology/National Institute of Heart Disease, Rawalpindi, Pakistan, from October 2017 to March 2018, and comprised patients who underwent coronary artery bypass graft surgery. Sternal wound healing as an outcome measure was assessed with nutritional status. Investigation of dietary data focussed on various food groups and their impact on wound healing. Data was analysed using SPSS 21.
Of the 330 patients, 16 (4.8%) died within hospital. The final sample, as such, comprised 314(95.2%) patients; 273 (86.9%) males and 42 (13.1%) females, with an overall mean age of 56.6±8.3 years. The mean body mass index was 26.9±4.3kg/m². There was non-significant relationship between body mass index and wound healing (p>0.05). Significant relationship was observed between albumin, blood glucose and wound healing (p<0.05).
Low levels of albumin and poor blood glucose control before surgery was found to be associated with delayed wound healing. Nutritional intervention prior to coronary artery bypass graft surgery may lead to reduced risk and complications during / after surgery.
评估行冠状动脉旁路移植术患者的术前营养状况及其对伤口愈合的影响。
本研究为在巴基斯坦拉瓦尔品第武装部队心脏病学研究所/国家心脏病研究所开展的基于医院的前瞻性研究，研究对象为行冠状动脉旁路移植术的患者。采用营养状况评估胸骨伤口愈合作为结局指标。饮食数据的调查侧重于各种食物组及其对伤口愈合的影响。使用 SPSS 21 进行数据分析。
330 例患者中，16 例（4.8%）在院内死亡。因此，最终样本包括 314 例（95.2%）患者；273 例（86.9%）为男性，42 例（13.1%）为女性，平均年龄为 56.6±8.3 岁。平均体重指数为 26.9±4.3kg/m²。体重指数与伤口愈合之间无显著关系（p>0.05）。白蛋白、血糖与伤口愈合之间存在显著关系（p<0.05）。
术前白蛋白水平低和血糖控制不佳与伤口愈合延迟有关。冠状动脉旁路移植术前进行营养干预可能会降低手术期间/之后的风险和并发症。
