Fan M Y, Wang J G, Jiang Y X, Zong D G, Lenz B, Walker D H
J Clin Microbiol. 1987 Apr;25(4):628-32. doi: 10.1128/jcm.25.4.628-632.1987.
Investigation of patients, healthy persons, and ticks in Jinghe County, Xinjiang Uygur Autonomous Region, People's Republic of China, for evidence of spotted fever group (SFG) rickettsiosis demonstrated strong evidence for a high prevalence of pathogenic SFG rickettsiae. Antibodies to SFG rickettsiae were detected in 62.5% of healthy subjects tested by enzyme-linked immunosorbent assay and 20% tested by complement fixation test. Two febrile patients were documented as having acute spotted fever rickettsiosis by complement fixation seroconversion. One, and 11-year-old Kazakh boy with eschar and regional lymphadenopathy, had an SFG rickettsia (An strain) isolated from his blood. A hemolymph test revealed that 20% of ticks contained rickettsiae. Two strains of SFG rickettsiae were isolated from male and female Dermacentor nuttalli ticks. The human SFG rickettsial isolate is the first to be obtained in the People's Republic of China.
对中华人民共和国新疆维吾尔自治区精河县的患者、健康人及蜱进行调查，以寻找斑点热群（SFG）立克次体病的证据，结果显示有强有力的证据表明致病性SFG立克次体的高流行率。通过酶联免疫吸附测定法检测的健康受试者中，62.5%检测到SFG立克次体抗体，通过补体结合试验检测的受试者中，20%检测到该抗体。两名发热患者通过补体结合血清转化记录为患有急性斑点热立克次体病。一名11岁哈萨克族男孩有焦痂和局部淋巴结病，从其血液中分离出一株SFG立克次体（An株）。血淋巴检测显示，20%的蜱含有立克次体。从雄性和雌性草原革蜱中分离出两株SFG立克次体。人类SFG立克次体分离株是在中华人民共和国首次获得的。
