National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London W12 0HS, UK.
National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London W12 0HS, UK.
Card Electrophysiol Clin. 2022 Jun;14(2):345-355. doi: 10.1016/j.ccep.2022.01.002.
Conduction system pacing avoids the potential deleterious effects of right ventricular pacing in patients with bradycardia and provides an alternative approach to cardiac resynchronization therapy. We focus on the available observational and randomized evidence and review studies supporting the safety, feasibility, and physiologic promise of conduction system approaches. We evaluate the randomized data generated from the available clinical trials of conduction system pacing, which have led to the recent inclusion of CSP in international guidelines. The scope for future randomized trials will building on the physiologic promise of conduction system approaches and offering information on clinical end points is explored.
心脏传导系统起搏避免了右心室起搏在心动过缓患者中的潜在有害影响，并为心脏再同步治疗提供了一种替代方法。我们重点关注现有的观察性和随机证据，并综述了支持心脏传导系统方法的安全性、可行性和生理潜力的研究。我们评估了来自心脏传导系统起搏现有临床试验的随机数据，这些数据导致了最近将 CSP 纳入国际指南。探讨了未来基于心脏传导系统方法的生理潜力的随机试验的范围，并提供了有关临床终点的信息。
