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开放性 IV 型胸腹主动脉瘤修复:苏格兰国家服务 22 年的经验。

Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service.

机构信息

Scottish National Service for Thoracoabdominal Aneurysms, Royal Infirmary of Edinburgh, Edinburgh, UK.

出版信息

Br J Surg. 2022 Jul 15;109(8):711-716. doi: 10.1093/bjs/znac049.

Abstract

BACKGROUND

Since 1999, the Scottish National Service for Thoracoabdominal Aneurysms has offered repair of thoracoabdominal aneurysms (TAAAs) to a population of 5.5 million people. The open operation most commonly performed by the service is the extent IV TAAA repair.

METHODS

All extent IV open TAAA repairs performed at the Scottish National Service for TAAAs from June 1999 until April 2021 were evaluated for clinical features, technical details, and clinical outcomes. The primary outcome measure was 30-day mortality; secondary outcomes included short-term (90 days, 6 months, 1 and 2 years) and long-term (5 and 10 years) survival, perioperative complications, and reintervention. Survival was assessed using Kaplan-Meier analysis.

RESULTS

Some 248 patients underwent extent IV TAAA repair, with elective surgery in 204 (82.3 per cent). A totally abdominal transperitoneal approach was used for all patients, with a median visceral ischaemia time of 40 (i.q.r. 35-48) min. Overall, 18 patients (7.3 per cent) died within 30 days. The proportion of patients surviving at 90 days, 6 months, 1, 2, 5, and 10 years was 0.91, 0.90, 0.89, 0.85, 0.72, and 0.41, respectively. Ten patients (4.0 per cent) required a reintervention while in hospital, four (1.6 per cent) experienced permanent spinal cord ischaemia, 19 (7.9 per cent) required temporary renal replacement therapy (RRT), and four (1.6 per cent) required permanent RRT.

CONCLUSION

Open extent IV TAAA repair performed in a high-volume national centre is associated with favourable short- and long-term survival, and acceptable complication rates.

摘要

背景

自 1999 年以来,苏格兰胸腹部主动脉瘤国家服务机构(Scottish National Service for Thoracoabdominal Aneurysms)为 550 万人口提供胸腹部主动脉瘤(thoracoabdominal aneurysms,TAAAs)修复手术。该服务机构最常进行的开放式手术是 IV 型 TAAA 修复。

方法

评估了 1999 年 6 月至 2021 年 4 月期间在苏格兰 TAAA 国家服务机构进行的所有 IV 型开放性 TAAA 修复的临床特征、技术细节和临床结果。主要观察指标是 30 天死亡率;次要结果包括短期(90 天、6 个月、1 年和 2 年)和长期(5 年和 10 年)生存率、围手术期并发症和再次干预。使用 Kaplan-Meier 分析评估生存率。

结果

共有 248 例患者接受了 IV 型 TAAA 修复,其中 204 例(82.3%)为择期手术。所有患者均采用完全经腹部腹膜后入路,内脏缺血时间中位数为 40(四分位距 35-48)分钟。总体而言,30 天内有 18 例(7.3%)患者死亡。90 天、6 个月、1 年、2 年、5 年和 10 年的生存率分别为 0.91、0.90、0.89、0.85、0.72 和 0.41。10 例(4.0%)患者在住院期间需要再次干预,4 例(1.6%)发生永久性脊髓缺血,19 例(7.9%)需要临时肾脏替代治疗(RRT),4 例(1.6%)需要永久性 RRT。

结论

在高容量的国家中心进行开放性 IV 型 TAAA 修复与良好的短期和长期生存率以及可接受的并发症发生率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3f1/10364699/927d9fb82610/znac049f1.jpg

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