Department of Neurosurgery, University of California, 200 W. Arbor Drive #8893, USA.
Department of Neurscience & Experimental Therapeutics, Albany Medical College, Albany, NY, USA.
Neurosurg Clin N Am. 2022 Jul;33(3):275-279. doi: 10.1016/j.nec.2022.02.005.
Chronic pain is a leading cause of disability in the United States. Limited efficacy associated with pharmacologic management and surgical interventions in refractory patients has led to further exploration of cognitive and behavioral interventions as both an adjunctive and primary therapeutic modality. Mindfulness-based meditation has shown to be effective in reducing pain in randomized studies of chronic pain patients as well as models of experimentally induced pain in healthy participants. These studies have revealed specific neural mechanisms which may explain both short-term and sustained pain relief associated with mindfulness-based interventions.
慢性疼痛是导致美国残疾的主要原因之一。在难治性患者中，药物治疗和手术干预的效果有限，这促使人们进一步探索认知和行为干预作为辅助和主要治疗方式。基于正念的冥想在慢性疼痛患者的随机研究以及健康参与者的实验性诱发疼痛模型中均显示出有效减轻疼痛的效果。这些研究揭示了与基于正念的干预相关的短期和持续缓解疼痛的特定神经机制。
