Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.
Department of Cognitive Science, University of California San Diego, La Jolla, CA, USA.
Curr Pain Headache Rep. 2020 Aug 17;24(10):56. doi: 10.1007/s11916-020-00890-8.
This review examines recent (2016 onwards) neuroscientific findings on the mechanisms supporting mindfulness-associated pain relief. To date, its clear that mindfulness lowers pain by engaging brain processes that are distinct from placebo and vary across meditative training level. Due to rapid developments in the field of contemplative neuroscience, an update review on the neuroimaging studies focused on mindfulness, and pain is merited.
Mindfulness-based therapies produce reliably reductions in a spectrum of chronic pain conditions through psychological, physiological, and neural mechanisms supporting the modulation of evaluation and appraisal of innocuous and noxious sensory events. Neuroimaging and randomized control studies confirm that mindfulness meditation reliably reduces experimentally induced and clinical pain by engaging multiple, unique, non-opioidergic mechanisms that are distinct from placebo and which vary across meditative training level. These promising findings underscore the potential of mindfulness-based approaches to produce long-lasting improvements in pain-related symptomology.
本综述探讨了最近（2016 年以后）关于支持正念相关疼痛缓解的机制的神经科学发现。迄今为止，很明显，正念通过参与不同于安慰剂的大脑过程来降低疼痛，并且在冥想训练水平上有所不同。由于沉思神经科学领域的快速发展，值得对专注于正念和疼痛的神经影像学研究进行更新综述。
通过支持对无害和有害感觉事件的评价和评价的心理、生理和神经机制，正念疗法可靠地减少了一系列慢性疼痛病症。神经影像学和随机对照研究证实，正念冥想通过参与多种独特的、非阿片类的机制，可靠地减轻实验诱导和临床疼痛，这些机制与安慰剂不同，并且在冥想训练水平上有所不同。这些有希望的发现强调了基于正念的方法在改善与疼痛相关的症状方面具有潜在的长期效果。
