Department of Neurosciences, Spectrum Health Medical Group, Grand Rapids, MI, USA; Michigan State University, Grand Rapids, MI, USA.
Department of Neurosciences, Spectrum Health Medical Group, Grand Rapids, MI, USA; Michigan State University, Grand Rapids, MI, USA.
Neurosurg Clin N Am. 2022 Jul;33(3):297-303. doi: 10.1016/j.nec.2022.02.008. Epub 2022 May 26.
Most currently available neuromodulation techniques for pain work through an open-loop system. The distance between the epidural space and the target of the stimulation in a dynamic body can change because of physiologic conditions. The closed-loop system in spinal cord neuromodulation consists of an integrated system that records real-time electrophysiological activity in the form of evoked compound action potentials and uses it in a feedback mechanism to adjust stimulus output. Wearables represent newly developed technologies that have gained traction in recent years. Their application in pain management is still developing but promising.
目前大多数用于疼痛的神经调节技术都是通过开环系统实现的。在动态身体中，硬膜外腔和刺激目标之间的距离可能会因生理状况而发生变化。脊髓神经调节中的闭环系统由一个集成系统组成，该系统以诱发复合动作电位的形式实时记录电生理活动，并将其用于反馈机制中，以调整刺激输出。可穿戴设备是近年来新兴的技术，已经引起了人们的关注。它们在疼痛管理中的应用尚在发展中，但前景广阔。
