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艾滋病病毒/艾滋病患者的生存相关因素:2011年至2019年在伊朗克尔曼沙赫的一项回顾性队列研究。

Survival-related Factors in HIV/AIDS Patients: A Retrospective Cohort Study from 2011 to 2019 in Kermanshah, Iran.

作者信息

Lorestani Roya Chegene, Kazemisafa Narges, Rostamian Mosayeb, Akya Alisha, Rezaeian Shahab, Bashiri Homayoon, Jasemi Seyed Vahid, Ghadiri Keyghobad

机构信息

Infectious Diseases Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Curr HIV Res. 2022;20(5):419-427. doi: 10.2174/1570162X20666220617141619.

Abstract

INTRODUCTION

Accurate evaluation of the survival rate among HIV-positive populations is pivotal for HIV management.

OBJECTIVE

This study aimed to investigate the survival rate and potential survival-related factors in HIV/AIDS patients from 2011 to 2019 in the city of Kermanshah in the west of Iran.

METHODS

In this study, 915 HIV-positive patients registered by the Kermanshah Behavioral diseases counseling center were surveyed from 2011 to 2019. The proper data on the survival factors were extracted and statistically analyzed by reading the patients' files.

RESULTS

Of 915 patients, 220 (24%) died. The one-year, five-year, and ten-year survival rates were 84%, 72%, and 62%, respectively. There was a significant relationship between the survival rate and many other parameters, including treatment variables, CD T cell count, the way of HIV transmission, level of education, gender, and marital status. Over time, the timely initiation of treatment has increased. The data also showed that HIV transmission through drug injection has decreased, while the sexual transmission of HIV has increased.

CONCLUSION

The results showed that the survival rate of HIV patients has increased in recent years due to the appropriate treatment. The highest risk factor of death was for people with low CD T cell count, lack of antiretroviral therapy, low level of education, male gender, and people who inject drugs. These people need more attention to get tested for HIV- related indexes and to receive proper treatment.

摘要

引言

准确评估艾滋病毒阳性人群的生存率对艾滋病毒管理至关重要。

目的

本研究旨在调查2011年至2019年伊朗西部克尔曼沙赫市艾滋病毒/艾滋病患者的生存率及潜在的生存相关因素。

方法

本研究对2011年至2019年在克尔曼沙赫行为疾病咨询中心登记的915名艾滋病毒阳性患者进行了调查。通过查阅患者档案提取生存因素的相关数据并进行统计分析。

结果

915名患者中,220人(24%)死亡。一年、五年和十年生存率分别为84%、72%和62%。生存率与许多其他参数之间存在显著关系,包括治疗变量、CD4 T细胞计数、艾滋病毒传播方式、教育程度、性别和婚姻状况。随着时间的推移,治疗的及时启动有所增加。数据还显示,通过注射毒品传播艾滋病毒的情况有所减少,而艾滋病毒的性传播有所增加。

结论

结果表明,由于适当的治疗,近年来艾滋病毒患者的生存率有所提高。死亡的最高风险因素是CD4 T细胞计数低、缺乏抗逆转录病毒治疗、教育程度低、男性以及注射毒品者。这些人群需要更多关注,以便进行艾滋病毒相关指标检测并接受适当治疗。

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