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在患者护理背景下开展转化研究。

Conducting Translational Research in the Context of Patient Care.

作者信息

Greer Brian D, Fisher Wayne W, Fuhrman Ashley M, Mitteer Daniel R

机构信息

Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ USA.

出版信息

Perspect Behav Sci. 2022 May 2;45(2):383-398. doi: 10.1007/s40614-022-00333-2. eCollection 2022 Jun.

Abstract

Although much has been written on the importance of translational research for bridging the continuum of basic science to clinical practice, few authors have described how such work can be carried out practically when working with patient populations in the context of ongoing clinical service delivery, where the priorities for patient care can sometimes conflict with the methods and goals of translational research. In this article, we explore some of the considerations for conducting this type of work while balancing clinical responsibilities that ensure high-quality patient care. We also discuss strategies we have found to jointly facilitate translational research and improve routine, clinical service delivery. A primary goal of this article is to encourage others working in applied settings to contribute to the increasingly important role that translational research plays in our science and practice by helping to better characterize and potentially lessen or remove barriers that may have impeded such investigations in the past.

摘要

尽管已经有很多关于转化研究对于弥合基础科学与临床实践之间差距的重要性的论述,但很少有作者描述在持续的临床服务提供背景下与患者群体合作时,如何实际开展此类工作,因为患者护理的优先事项有时可能与转化研究的方法和目标相冲突。在本文中,我们探讨了在平衡确保高质量患者护理的临床责任的同时开展这类工作的一些注意事项。我们还讨论了我们发现的共同促进转化研究和改善常规临床服务提供的策略。本文的一个主要目标是鼓励在应用环境中工作的其他人,通过帮助更好地描述并可能减少或消除过去可能阻碍此类研究的障碍,为转化研究在我们的科学和实践中日益重要的作用做出贡献。

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