Vaishnavi C, Kaur S, Kumar B, Kaur H, Ganguly N K
Indian J Lepr. 1986 Oct-Dec;58(4):522-9.
Mycobacterium leprae infection was produced through the footpads in normal and immunosuppressed mice. Circulating immune complexes were detected by specific binding test and by conglutinin binding assay for specific and total immune complexes respectively in the sera of these mice during different periods of infection. Out of the total 30 samples tested from the infected groups, 3 were positive by specific binding test and 5 by conglutinin binding ELISA. The implications of the findings in relation to human leprosy are discussed.
通过足垫接种在正常和免疫抑制小鼠中引发麻风分枝杆菌感染。在这些小鼠感染的不同阶段，分别通过特异性结合试验以及针对特异性和总免疫复合物的胶固素结合测定法，检测血清中的循环免疫复合物。在从感染组检测的总共30个样本中，特异性结合试验有3个呈阳性，胶固素结合ELISA有5个呈阳性。讨论了这些发现与人类麻风病的相关性。
