Di Stefano Michele, Grandi Giacomo, Bonaso Vera, Pagani Elisabetta, Corazza Gino Roberto, Di Sabatino Antonio
1st Department of Internal Medicine, IRCCS "S. Matteo" Hospital Foundation, Pavia, Italy.
University of Pavia, Italy.
EXCLI J. 2022 Mar 24;21:651-655. doi: 10.17179/excli2022-4838. eCollection 2022.
Eosinophilic esophagitis (EoE) is a type-2 mediated, chronic inflammatory disease showing an increase of both incidence and prevalence. Early diagnosis is mandatory, to prevent fibrostenotic complication of the disease. Due to the low sensitivity of the classic endoscopic features of the disease, a strong clinical suspicion should drive the decision to collect mucosal biopsies of the esophagus. We describe the case of an atopic patient suffering from dysphagia with normal esophageal mucosa and frank histological hallmarks of the disease.
嗜酸性粒细胞性食管炎（EoE）是一种2型介导的慢性炎症性疾病，其发病率和患病率均呈上升趋势。早期诊断至关重要，以预防该疾病的纤维狭窄并发症。由于该疾病经典内镜特征的敏感性较低，强烈的临床怀疑应促使决定采集食管黏膜活检样本。我们描述了一例患有吞咽困难的特应性患者，其食管黏膜正常，但具有该疾病明确的组织学特征。
