糖尿病患者的步态参数与周围神经病变：一项荟萃分析。
Gait Parameters and Peripheral Neuropathy in Patients With Diabetes: A Meta-Analysis.
机构信息
Department of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Department of Endocrinology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
出版信息
Front Endocrinol (Lausanne). 2022 Jun 1;13:891356. doi: 10.3389/fendo.2022.891356. eCollection 2022.
OBJECTIVE
To investigate the relationship between diabetic peripheral neuropathy (DPN) and gait abnormality in diabetic patients.
METHODS
Related research concerning the gait of diabetic patients with and without DPN was collected and analyzed by searching PubMed, Embase, and Web of Science. Statistical analysis was performed by using RevMan 5.3 software.
RESULTS
Twenty-one studies were included in this meta-analysis, consisting of 499 diabetic neuropathy patients and 467 diabetes controls without neuropathy. Meta-analysis results showed lower gait velocity, shorter stride length, longer stride time, longer stance time, and higher maximum knee extension moment in the DPN group, compared with their counterparts.
CONCLUSION
Among diabetic patients, those complicated with DPN possess lower gait velocity, shorter stride length, longer stride time, longer stance time, and higher maximum knee extension moment.
目的
探讨糖尿病患者糖尿病周围神经病变（DPN）与步态异常的关系。
方法
检索 PubMed、Embase 和 Web of Science 数据库，收集并分析有关糖尿病伴或不伴 DPN 患者步态的相关研究。采用 RevMan 5.3 软件进行统计学分析。
结果
本荟萃分析纳入 21 项研究，共纳入 499 例糖尿病神经病变患者和 467 例无神经病变的糖尿病对照者。Meta 分析结果显示，DPN 组患者的步速较低，步长较短，步时较长，支撑时间较长，最大膝关节伸展力矩较高。
结论
在糖尿病患者中，合并 DPN 的患者步速较低，步长较短，步时较长，支撑时间较长，最大膝关节伸展力矩较高。
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