Kalmanson Olivia A, Misch Emily S, Terella Adam
University of Colorado School of Medicine, Department of Otolaryngology, 12631 E 17th Ave, Aurora, CO 80045, United States.
JPRAS Open. 2022 May 24;33:37-41. doi: 10.1016/j.jpra.2022.05.011. eCollection 2022 Sep.
Hyaluronic acid-based filler is the most popular injectable augmentation preparation due to its efficacy and safety compared to other injection fillers. The complication of infected filler is known, but it is unknown exactly how long filler persists prior to reabsorption. A case was presented of filler-exacerbated facial cellulitis that occurred 2.5 years after hyaluronic acid-based filler administration. The presence of residual filler was confirmed with magnetic resonance imaging, suggesting that hyaluronic acid-based fillers may persist longer than previously thought and act as a reservoir for regional bacterial infections refractory to antibiotics.
与其他注射填充剂相比，基于透明质酸的填充剂因其有效性和安全性而成为最受欢迎的可注射填充制剂。填充剂感染的并发症是已知的，但尚不清楚填充剂在重新吸收之前确切会持续多长时间。本文报告了1例在注射基于透明质酸的填充剂2.5年后发生的填充剂加重面部蜂窝织炎病例。通过磁共振成像证实了残留填充剂的存在，这表明基于透明质酸的填充剂可能比之前认为的持续时间更长，并可作为对抗生素难治的局部细菌感染的储存库。
