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急性贝尔氏麻痹的“镜像效应加方案”:一项为期 1 年随访的随机对照试验。

The "Mirror Effect Plus Protocol" for acute Bell's palsy: A randomized controlled trial with 1-year follow-up.

机构信息

Hôpital Maisonneuve-Rosemont, Montréal, Québec, Canada.

Centre de recherche du Centre intégré Universitaire de santé et services sociaux du Nord-de-l'île-de-Montréal, Hôpital du Sacré-Cœur de Montréal, Montréal, Québec, Canada.

出版信息

Clin Rehabil. 2022 Oct;36(10):1292-1304. doi: 10.1177/02692155221107090. Epub 2022 Jun 19.

DOI:10.1177/02692155221107090
PMID:35722671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9420890/
Abstract

OBJECTIVE

To study the effects of the "Mirror Effect Plus Protocol" (MEPP) on global facial function in acute and severe Bell's Palsy.

DESIGN

Single blind and randomized controlled trial to compare the effects of basic counseling (control group) versus MEPP (experimental group) over one year.

SETTING

Outpatient clinic following referrals from Emergency or Otorhinolaryngology Departments.

SUBJECTS

40 patients ( = 20 per group) with moderately severe to total palsy who received standard medication were recruited within 14 days of onset. Baseline characteristics were comparable between the groups.

INTERVENTIONS

The experimental group received the MEPP program (motor imagery + manipulations + facial mirror therapy) while the control group received basic counseling. Both groups met the clinician monthly until 6 months and at one-year post-onset for assessments.

OUTCOME MEASURES

Facial symmetry, synkinesis, and quality of life were measured using standardized scales. Perceived speech intelligibility was rated before and after therapy by naïve judges.

RESULTS

Descriptive statistics demonstrated improvements in favor of the MEPP for each measured variable. Significant differences were found for one facial symmetry score (House-Brackmann 2.0 mean (SD) = 7.40 (3.15) for controls versus 5.1 (1.44) for MEPP), for synkinesis measures ( = 0.008) and for quality-of-life ratings (mean (SD) score = 83.17% (17.383) for controls versus 98.36% (3.608) for MEPP ( = 0.002)). No group difference was found for perceived speech intelligibility.

CONCLUSION

The MEPP demonstrates promising long-term results when started during the acute phase of moderately severe to total Bell's Palsy.

摘要

目的

研究“镜像效应加方案”(MEPP)对急性和重度贝尔麻痹的整体面部功能的影响。

设计

单盲、随机对照试验,比较基本咨询(对照组)与 MEPP(实验组)在一年中的效果。

设置

从急诊或耳鼻喉科转介的门诊。

对象

40 名(每组 20 名)中度至重度面瘫患者,在发病后 14 天内接受标准药物治疗。两组患者的基线特征相似。

干预

实验组接受 MEPP 方案(运动想象+操作+面部镜像治疗),对照组接受基本咨询。两组患者每月与临床医生见面,直至发病后 6 个月和 1 年进行评估。

结局测量

采用标准化量表测量面部对称性、联带运动和生活质量。治疗前后由不知情的评判者对感知言语清晰度进行评分。

结果

描述性统计显示,MEPP 对每种测量变量均有改善。在一个面部对称性评分(House-Brackmann 2.0 平均值(SD)=对照组 7.40(3.15),实验组 5.1(1.44))、联带运动测量( = 0.008)和生活质量评分(平均值(SD)=对照组 83.17%(17.383),实验组 98.36%(3.608))方面,实验组与对照组存在显著差异( = 0.002)。在感知言语清晰度方面,两组间无差异。

结论

在中度至重度贝尔麻痹的急性期开始时使用 MEPP 可获得有前景的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ed/9420890/6166e6a81d53/10.1177_02692155221107090-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ed/9420890/f8e50ed8ebb8/10.1177_02692155221107090-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ed/9420890/6166e6a81d53/10.1177_02692155221107090-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ed/9420890/f8e50ed8ebb8/10.1177_02692155221107090-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ed/9420890/6166e6a81d53/10.1177_02692155221107090-fig2.jpg

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本文引用的文献

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Facial Plast Surg Aesthet Med. 2022 Jan-Feb;24(1):63-65. doi: 10.1089/fpsam.2020.0608. Epub 2021 Apr 13.
2
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Acta Otolaryngol. 2021 Feb;141(2):203-208. doi: 10.1080/00016489.2020.1842905. Epub 2020 Nov 20.
3
Mirror Book Therapy for the treatment of Idiopathic Facial Palsy.
促进或阻碍面部康复网络工具 MEPP 2.0 使用的因素:魁北克省卫生系统的比较研究。
BMC Health Serv Res. 2024 Oct 18;24(1):1256. doi: 10.1186/s12913-024-11628-2.
4
The Use of Mirror Therapy in Peripheral Seventh Nerve Palsy: A Systematic Review.镜像疗法在周围性面神经麻痹中的应用:一项系统评价
Brain Sci. 2024 May 23;14(6):530. doi: 10.3390/brainsci14060530.
5
Treatment Approaches for Altered Facial Expression: A Systematic Review in Facioscapulohumeral Muscular Dystrophy and Other Neurological Diseases.面部表情改变的治疗方法:面肩肱型肌营养不良及其他神经系统疾病的系统评价
J Neuromuscul Dis. 2024;11(3):535-565. doi: 10.3233/JND-230213.
6
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JMIR Res Protoc. 2023 Jul 7;12:e47709. doi: 10.2196/47709.
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4
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7
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8
A Machine Learning Approach for Automated Facial Measurements in Facial Palsy.一种用于面神经麻痹自动面部测量的机器学习方法。
JAMA Facial Plast Surg. 2018 Jul 1;20(4):335-337. doi: 10.1001/jamafacial.2018.0030.
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10
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