The Affiliated Lianyungang Oriental Hospital, Kangda College of Nanjng Medical University, Lianyungang, Jiangsu Province, China.
The Affiliated Lianyungang Oriental Hospital, Xuzhou Medical University, Lianyungang, Jiangsu Province, China.
PeerJ. 2022 Jun 15;10:e13445. doi: 10.7717/peerj.13445. eCollection 2022.
The aim of this study was to investigate the effect of skeletal sarcopenia on the prognosis of intertrochanteric fracture in the elderly.
We collected information on 144 patients with femoral intertrochanteric fracture (FIF). The influence of sarcopenia on the chance of death was determined using binary Probit regression analysis. For additional analysis, the Chow test was utilized to select the best distinguishing node in the instrumental activities of daily living (IADL) score. We looked for characteristics that were linked to a higher probability of death and a poor IADL outcome within 1 year. The data collected above were analyzed using logistic regression analysis. The internal calibration degree and model validity were assessed by GiViTI calibration.
Sarcopenia, EuroQol-5D 1 month score, age, gender, and hypertension were identified as risk factors for death in older patients with FIF within a year by logistic regression analysis. Sarcopenia, psychotropics, BMI, and length of hospital stay were all found to be risk factors for poor IADL outcomes ( < 0.1). The calibration curves indicated that the anticipated and actual probabilities of these two models were very close. The study's reliability coefficient was 0.671, showing a satisfactory level of reliability.
In elderly patients with FIF, sarcopenia, EuroQol-5D score, age, gender, and hypertension were risk factors for death; sarcopenia, hospital stay length, BMI were risk factors for poor quality of life.
本研究旨在探讨骨骼肌减少症对老年股骨转子间骨折预后的影响。
我们收集了 144 例股骨转子间骨折（FIF）患者的信息。使用二元 Probit 回归分析确定肌减少症对死亡几率的影响。为了进一步分析，采用 Chow 检验选择工具性日常生活活动（IADL）评分的最佳区分节点。我们寻找与 1 年内死亡几率较高和 IADL 结局较差相关的特征。使用逻辑回归分析对上述数据进行分析。使用 GiViTI 校准评估内部校准程度和模型有效性。
逻辑回归分析表明，肌减少症、EuroQol-5D 1 个月评分、年龄、性别和高血压是老年 FIF 患者一年内死亡的危险因素。肌减少症、精神药物、BMI 和住院时间均是 IADL 结局较差（<0.1）的危险因素。校准曲线表明，这两个模型的预期和实际概率非常接近。研究的可靠性系数为 0.671，显示出令人满意的可靠性。
在老年股骨转子间骨折患者中，肌减少症、EuroQol-5D 评分、年龄、性别和高血压是死亡的危险因素；肌减少症、住院时间长度、BMI 是生活质量较差的危险因素。
