Issabek Aisha U, Orynbayev Mukhit B, Sultankulova Kulyaisan T, Amirgazin Asylulan, Zakarya Kunsulu D, Omarova Zamira, Chervyakova Olga V
Research Institute for Biological Safety Problems, Gvardeyskiy, Republic of Kazakhstan.
National Center for Biotechnology, Nur-Sultan, Republic of Kazakhstan.
Microbiol Resour Announc. 2022 Jul 21;11(7):e0038022. doi: 10.1128/mra.00380-22. Epub 2022 Jun 21.
Here, we present the coding sequence of the genome of the recombinant lumpy skin disease virus (LSDV) Atyrau-5BJN(IL18), obtained by knocking out four genes in the genome of a virulent field LSDV isolate. Genome sequencing confirmed the deletion of genes and the insertion of a foreign sequence in the viral genome.
在此,我们展示了重组牛结节性皮肤病病毒(LSDV)阿特劳 - 5BJN(IL18)的基因组编码序列,该病毒是通过敲除一株强毒力的田间LSDV分离株基因组中的四个基因获得的。基因组测序证实了病毒基因组中基因的缺失和外源序列的插入。