Patel Madhav R, Jacob Kevin C, Chavez Frank A, DesLaurier Justin T, Pawlowski Hanna, Prabhu Michael C, Vanjani Nisheka N, Singh Kern
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA
Int J Spine Surg. 2022 Jun 20;16(4):595-604. doi: 10.14444/8309.
Increased morbidity associated with obesity imposes a greater financial burden on companies that provide insurance to their employees. Few studies have investigated the relationship between body mass index (BMI) and patient-reported outcome measures (PROMs) for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) in the workers' compensation (WC) population.
WC patients who underwent a primary, single-level MIS TLIF were included/grouped according to BMI: nonobese (<30 kg/m); obese I (≥30, <35 kg/m); severe + morbid (≥35). PROMs were collected pre- and postoperatively: visual analog scale (VAS), Oswestry Disability Index (ODI), 12-Item Short Form (SF-12) physical composite score (PCS), and Patient-Reported Outcome Measurement Information System physical function (PROMIS-PF). BMI predictive power grouping on PROMs was evaluated using simple linear regression. Established minimum clinically important difference values were used to compute achievement rates across PROMs using logistic regression.
A total of 116 nonobese, 70 obese I, and 61 severe + morbid patients were included. Demographics among BMI grouping significantly differed in gender, hypertensive status, and American Society of Anesthesiologists score ( ≤ 0.037, all). Operative time was significantly different in perioperative values among BMI grouping ( ≤ 0.001). Increased BMI was significantly associated with greater VAS back at 12 weeks and 2 years ( ≤ 0.026, all), greater ODI preoperatively at 12 weeks and 6 months ( ≤ 0.015, all), and decreased PROMIS-PF at 12 weeks ( ≤ 0.011, all). Mean PROMs between obese I and severe + morbid cohorts differed in SF-12 PCS at 12 weeks, only ( = 0.050). ODI overall was the only parameter for which minimum clinically important difference was achieved among BMI cohorts ( ≤ 0.023).
WC patients with increased BMI were more likely to develop significant back pain and disability at numerous postoperative timepoints compared with nonobese individuals. Our findings highlight the weight management importance within WC population to minimize back pain and disability following MIS TLIF, but provide a sense of reassurance with comparable clinical improvement regardless of BMI.
When considering the effect of weight, surgeons may incorporate these findings in managing patient expectations in the WC population undergoing lumbar spine surgery.
肥胖相关的发病率增加给为员工提供保险的公司带来了更大的经济负担。很少有研究调查体重指数(BMI)与工伤赔偿(WC)人群中微创经椎间孔腰椎椎间融合术(MIS TLIF)患者报告结局指标(PROMs)之间的关系。
纳入接受初次单节段MIS TLIF的WC患者,并根据BMI进行分组:非肥胖(<30 kg/m²);肥胖I级(≥30,<35 kg/m²);重度及病态肥胖(≥35)。在术前和术后收集PROMs:视觉模拟量表(VAS)、Oswestry功能障碍指数(ODI)、12项简明健康调查(SF-12)身体综合评分(PCS)以及患者报告结局测量信息系统身体功能(PROMIS-PF)。使用简单线性回归评估BMI对PROMs的预测能力分组。使用逻辑回归,根据既定的最小临床重要差异值计算各PROMs的达标率。
共纳入116例非肥胖患者、70例肥胖I级患者和61例重度及病态肥胖患者。BMI分组之间的人口统计学特征在性别、高血压状态和美国麻醉医师协会评分方面存在显著差异(均≤0.037)。BMI分组之间围手术期值的手术时间存在显著差异(≤0.001)。BMI增加与术后12周和2年时更大的VAS背痛显著相关(均≤0.026),术前12周和6个月时更大的ODI显著相关(均≤0.015),以及术后12周时PROMIS-PF降低显著相关(均≤0.011)。仅在术后12周时,肥胖I级和重度及病态肥胖队列之间的SF-12 PCS的平均PROMs存在差异(P = 0.050)。总体而言,ODI是BMI队列中唯一达到最小临床重要差异的参数(≤0.023)。
与非肥胖个体相比,BMI增加的WC患者在术后多个时间点更有可能出现明显的背痛和残疾。我们的研究结果强调了WC人群中体重管理对于将MIS TLIF术后背痛和残疾降至最低的重要性,但也表明无论BMI如何,临床改善情况相当,让人放心。
在考虑体重的影响时,外科医生可将这些发现纳入对接受腰椎手术的WC人群患者期望的管理中。