Division of Gastroenterology and Hepatology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Biostatistics Support Unit, Clinical Research Institute, American University of Beirut Medical Center, Beirut, Lebanon.
BMC Gastroenterol. 2022 Jun 21;22(1):301. doi: 10.1186/s12876-022-02374-y.
BACKGROUND/AIM: The ABC score is a new pre-endoscopic scoring system that was recently developed to accurately predict one-month mortality in upper and lower gastrointestinal bleeding (GIB). We aim to validate this new score on a cohort of Lebanese patients treated in a tertiary care center and to compare it to currently existing scores.
Adult patients admitted to the American University of Beirut Medical Center (AUBMC) with overt GIB between January 2013 and August 2020 were included. The area under receiver operating characteristic (AUROC) curves of the ABC score in predicting 30-day mortality was calculated using the SPSS software. Other optimal existing scores for predicting mortality (the Oakland score for lower GIB, the AIMS-65 and the Rockall scores for upper GIB)s were also assessed and compared to the ABC score.
A total of 310 patients were included in our study. For upper GIB, the ABC score showed good performance in predicting 30-day mortality (AUROC: 0.79), outperforming both the AIMS-65 score (AUROC 0.67, p < 0.001) and the Rockall score (AUROC: 0.62, p < 0.001). For lower GIB, the ABC score also had good performance which was comparable to the Oakland score (AUROC: 0.70 vs 0.56, p = 0.26).
In our cohort of patients, the ABC score demonstrated good performance in predicting 30-day mortality for patients with upper and lower GIB compared to other established risk scores, which may help guide management decisions. This simple and novel score provides valuable prognostic information for patients presenting with GIB and appears to be reproducible in different patient populations.
背景/目的:ABC 评分是一种新的内镜前评分系统,最近被开发出来以准确预测上消化道和下消化道出血(GIB)患者一个月的死亡率。我们旨在验证该新评分在一个接受三级护理中心治疗的黎巴嫩患者队列中的有效性,并将其与目前现有的评分进行比较。
纳入 2013 年 1 月至 2020 年 8 月期间因显性 GIB 入住贝鲁特美国大学医学中心(AUBMC)的成年患者。使用 SPSS 软件计算 ABC 评分预测 30 天死亡率的受试者工作特征(ROC)曲线下面积(AUROC)。还评估并比较了其他预测死亡率的最佳现有评分(下 GIB 的 Oakland 评分、上 GIB 的 AIMS-65 和 Rockall 评分)与 ABC 评分。
共有 310 例患者纳入本研究。对于上 GIB,ABC 评分在预测 30 天死亡率方面表现良好(AUROC:0.79),优于 AIMS-65 评分(AUROC 0.67,p<0.001)和 Rockall 评分(AUROC:0.62,p<0.001)。对于下 GIB,ABC 评分也表现良好,与 Oakland 评分相当(AUROC:0.70 与 0.56,p=0.26)。
在我们的患者队列中,与其他已建立的风险评分相比,ABC 评分在预测上 GIB 和下 GIB 患者 30 天死亡率方面表现良好,这可能有助于指导管理决策。这种简单而新颖的评分可提供有价值的预后信息,适用于 GIB 患者,并且似乎在不同的患者人群中具有可重复性。