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系统性硬皮病合并心动过速-心动过缓综合征:一例报告。

Systemic sclerosis and tachycardia-bradycardia syndrome: a case report.

机构信息

Mohammed V University of Rabat, Rabat, Morocco.

出版信息

J Med Case Rep. 2022 Jun 21;16(1):258. doi: 10.1186/s13256-022-03462-z.

Abstract

BACKGROUND

Systemic sclerosis is a multisystemic character autoimmune disease. It is characterized by vascular dysfunction and progressive fibrosis affecting mainly the skin but also different internal organs. All heart structures are commonly affected, including the pericardium, myocardium, and conduction system. However, tachycardia-bradycardia syndrome is not common in the literature as a cardiac complication of systemic sclerosis. Case presentation We report a case of tachycardia-bradycardia syndrome in a 46-year-old Moroccan woman followed for systemic sclerosis with cutaneous, vascular, and articular manifestations. The diagnosis was based mainly on patient-reported symptoms and electrocardiogram data. A permanent pacemaker was implanted, allowing the introduction of beta-blockers with good outcomes.

CONCLUSIONS

This case aims to show that even minor electrocardiogram abnormalities should be monitored in this group of patients, preferably by 24-hour ambulatory electrocardiogram because they could be a good indicator of the activity and progression of cardiac fibrosis.

摘要

背景

系统性硬化症是一种多系统特征自身免疫性疾病。其特征为血管功能障碍和进行性纤维化,主要影响皮肤,但也影响不同的内部器官。所有的心脏结构都常受影响,包括心包、心肌和传导系统。然而,心动过速-心动过缓综合征作为系统性硬化症的一种心脏并发症并不常见。

病例介绍

我们报告了一例 46 岁的摩洛哥女性系统性硬化症患者的心动过速-心动过缓综合征病例,该患者有皮肤、血管和关节表现。诊断主要基于患者的自述症状和心电图数据。植入了永久性起搏器,随后引入了β受体阻滞剂,取得了良好的效果。

结论

本病例旨在表明,即使是轻微的心电图异常也应在这组患者中进行监测,最好通过 24 小时动态心电图监测,因为它们可能是心脏纤维化活动和进展的良好指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd3d/9210766/4ad326961af2/13256_2022_3462_Fig1_HTML.jpg

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