Flachsenberger W A
J Toxicol Clin Toxicol. 1986;24(6):485-502. doi: 10.3109/15563658608995389.
The effects of crude blue-ringed octopus venom gland extract and tetrodotoxin (TTX) on anaesthetised rats and rabbits were studied. Paralysis of the respiratory musculature causing anoxia and cyanosis was overcome with positive, artificial respiration. The second lethal mechanism of the toxins: rapid and severe hypotension, had to be counteracted peripherally, since neural transmission had been drastically reduced by the toxins. Noradrenaline, d-amphetamine, phenylephrine and methoxamine, agonists acting on vascular adrenergic a-receptors, were tested.
研究了粗制蓝环章鱼毒腺提取物和河豚毒素（TTX）对麻醉大鼠和兔子的影响。通过积极的人工呼吸克服了导致缺氧和发绀的呼吸肌麻痹。毒素的第二种致死机制：迅速而严重的低血压，必须在外周进行对抗，因为毒素已使神经传递大幅减少。测试了去甲肾上腺素、右旋苯丙胺、去氧肾上腺素和甲氧明，这些都是作用于血管肾上腺素能α受体的激动剂。
