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评估参数成像显示的区域性壁运动异常评分与 CMR 所示 LGE 范围之间的关系。

Assessment of the relationship between regional wall motion abnormality score revealed by parametric imaging and the extent of LGE with CMR.

机构信息

University of Tunis El Manar, Higher Institute of Medical Technologies of Tunis, Laboratory of Biophysics and Medical Technology, Tunis, Tunisia.

Faculty of Medicine of Monastir, Medical Imaging Technology Lab - LTIM-LR12ES06, University of Monastir, 5019 Monastir, Tunisia; Gaspard-Monge Computer-science Laboratory, Paris-Est University, Mixed Unit CNRS-UMLV-ESIEE UMR8049, BP99, ESIEE Paris Cité Descartes, 93162 Noisy Le Grand, France.

出版信息

Clin Imaging. 2022 Sep;89:68-77. doi: 10.1016/j.clinimag.2022.05.007. Epub 2022 May 21.

Abstract

The aim of this study was to assess the relationship between left ventricular (LV) regional myocardial wall motion abnormality (WMA), revealed by visual interpretation of cardiac magnetic resonance (CMR) cine images together with the computed wall motion parametric image, and the transmural scar extent, as assessed by Late gadolinium Enhancement (LGE), in 40 patients. Each cine CMR short-axis loop was processed to compute a parametric image where each pixel represents the amplitude of the Hilbert transform of videointensity over time. Two expert radiologists blindly interpreted the cine CMR images in combination with the corresponding parametric image to assign a WMA score for each of the 16 myocardial sectors in which the LV myocardium was subdivided. Such score was compared per sector to the level of transmural scar extent obtained by LGE images. A total of 592 myocardial segments were analyzed. A significant decrease in regional wall motion was observed in sectors with LGE transmural hyperenhancement > 75% of tissue, as well as a correlation between parametric image amplitude and peak radial and circumferential strain, computed by feature tracking. The results showed a reduction in prediction error Lambda of WMA from LGE of 65%, and of LGE from WMA of 63%. In particular, the estimated probability of correct prediction of WMA from LGE was 76%, while that of LGE from WMA was 75%. The interpretation of myocardial viability by LGE images combined with the WMA information, derived from cine CMR and parametric images, could improve the clinical decision making process.

摘要

本研究旨在评估 40 例患者的左心室(LV)局部心肌壁运动异常(WMA)与透壁性瘢痕程度之间的关系,LV 局部心肌壁运动异常通过心脏磁共振(CMR)电影图像的视觉解释与计算壁运动参数图像共同揭示,透壁性瘢痕程度通过晚期钆增强(LGE)评估。对每个电影 CMR 短轴环进行处理,以计算出参数图像,其中每个像素代表视频强度随时间的希尔伯特变换幅度。两位经验丰富的放射科医生对电影 CMR 图像进行盲法解释,结合相应的参数图像,为 LV 心肌分为 16 个心肌扇区中的每个扇区分配 WMA 评分。根据 LGE 图像获得的透壁性瘢痕程度,对每个扇区的 WMA 评分进行比较。共分析了 592 个心肌节段。在 LGE 透壁高增强>75%组织的节段观察到局部壁运动明显下降,并且参数图像幅度与特征跟踪计算的径向和圆周应变峰值之间存在相关性。结果显示,从 LGE 预测 WMA 的预测误差 Lambda 降低了 65%,从 WMA 预测 LGE 的降低了 63%。特别是,从 LGE 预测 WMA 的正确预测概率为 76%,而从 WMA 预测 LGE 的正确预测概率为 75%。LGE 图像结合电影 CMR 和参数图像中的 WMA 信息来解释心肌活力,可能会改善临床决策过程。

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