Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, 20131, Thailand.
Pharmaceutical Innovations of Natural Products Unit (PhInNat), Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand.
Int J Clin Pharm. 2022 Aug;44(4):873-893. doi: 10.1007/s11096-022-01445-0. Epub 2022 Jun 23.
Levonorgestrel and ulipristal acetate are common emergency oral contraceptives (EOCs). Lack of knowledge and negative attitude toward EOCs pose barriers to the EOCs access and utilization.
This study aimed to summarize the studies on the knowledge and attitudes of healthcare providers and patients on the use of EOCs.
A systematic search was conducted from conception to April 2022 using the following databases: CINAHL Complete, MEDLINE, ScienceDirect, Scopus, and Thai Journal Online. Data were extracted independently and were meta-analyzed using DerSimonian and Laird method for the binary random-effects model.
121 articles with a total number of 92,484 participants were included. The awareness of levonorgestrel as an EOC was 66.7% while the awareness of ulipristal acetate as an EOC was 36.9%. EOCs users received EOC information mainly from the internet, media, and friends. We found that 32.2% of EOCs users and providers agreed that EOCs acted post-fertilization, and 39.8% of the prescribers know the correct time to take the pill postcoital. Negative attitudes toward EOC use were found in 25.4% of the participants. For example, 39.4% of the participants agreed that EOCs users had increased sexual activity.
The awareness of EOCs was low and misunderstandings or negative attitudes towards the use or prescription of EOCs were still prevalent. Educating healthcare providers, using media as educational tools, and improving education and economics can be useful in improving EOC users' awareness, knowledge, and attitude towards EOCs.
左炔诺孕酮和乌利司他是常见的紧急口服避孕药（EOC）。对 EOC 的了解不足和负面态度会对 EOC 的获取和使用造成障碍。
本研究旨在总结医疗保健提供者和患者对 EOC 使用的知识和态度的研究。
从概念到 2022 年 4 月，使用以下数据库进行系统搜索：CINAHL Complete、MEDLINE、ScienceDirect、Scopus 和泰国在线期刊。独立提取数据，并使用 DerSimonian 和 Laird 方法对二元随机效应模型进行荟萃分析。
共纳入 121 篇文章，总计 92484 名参与者。左炔诺孕酮作为 EOC 的知晓率为 66.7%，而乌利司他作为 EOC 的知晓率为 36.9%。EOC 使用者主要通过互联网、媒体和朋友获得 EOC 信息。我们发现，32.2%的 EOC 使用者和提供者认为 EOC 作用于受精后，39.8%的开方者知道性交后正确的服药时间。25.4%的参与者对 EOC 使用持负面态度。例如，39.4%的参与者认为 EOC 使用者的性行为增加。
EOC 的知晓率较低，对 EOC 的使用或处方的误解或负面态度仍然普遍存在。对医疗保健提供者进行教育、使用媒体作为教育工具以及改善教育和经济状况，有助于提高 EOC 使用者对 EOC 的认识、知识和态度。
