Hass Holger G, Seywald Marianne, Wöckel Achim, Muco Blerta, Tanriverdi Miro, Stepien Jürgen
Klinik Gais, Abteilung Onkologie, Dep. Innere Medizin, Gäbrisstrasse 1172, 9056, Gais, Switzerland.
Institut Für Rehabilitationsforschung Und Survivorship (IREFOS), 88175, Scheidegg, Germany.
Arch Gynecol Obstet. 2023 Mar;307(3):919-925. doi: 10.1007/s00404-022-06657-3. Epub 2022 Jun 22.
As a result of the cancer diagnosis and the mostly multimodal, stressful therapy, psychological distress is a common symptom in breast cancer patients. As part of this prospective study, 1400 patients who were admitted to the hospital for oncological rehabilitation were screened for distress and somatic, therapy-induced secondary disorders. Mean distress in the screened population was 5.6 ± 2.56 (range 0-10). In 942 cases (67.3%) a significant distress score (≥ 5) was detected and in 587 cases (41.9%) very high levels of distress (≥ 7) was observed. Psychological distress significantly correlated with younger age, presence of triple negative breast cancer (TNBC), tumor recurrence and metastasis, and inability to work. Treatment-induced side effects such as lymphedema, CIPN or extensive tumor resection (mastectomy) showed a (not significant) trend for higher distress. The high incidence of distress underscores the importance of psycho-oncological therapy offers and the great importance of occupational measures during oncological rehabilitation such as the importance of a successful return to work for a better quality of life in breast cancer patients.
由于癌症诊断以及大多采用的多模式、压力大的治疗方法，心理困扰是乳腺癌患者的常见症状。作为这项前瞻性研究的一部分，对1400名因肿瘤康复入院的患者进行了心理困扰以及躯体性、治疗引起的继发性疾病筛查。筛查人群的平均心理困扰评分为5.6±2.56（范围0 - 10）。在942例（67.3%）患者中检测到显著的心理困扰评分（≥5），在587例（41.9%）患者中观察到非常高的心理困扰水平（≥7）。心理困扰与年轻、三阴性乳腺癌（TNBC）的存在、肿瘤复发和转移以及无法工作显著相关。治疗引起的副作用如淋巴水肿、化疗引起的周围神经病变或广泛的肿瘤切除（乳房切除术）显示出（不显著的）心理困扰增加趋势。心理困扰的高发生率凸显了心理肿瘤治疗的重要性以及肿瘤康复期间职业措施的重要性，例如成功重返工作岗位对乳腺癌患者提高生活质量的重要性。
