基于任务的 fMRI 技术的针刺作用机制研究：范围综述方案。
Acupuncture mechanism studies employing task-based fMRI: a scoping review protocol.
机构信息
Department of Acupuncture, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310007, Zhejiang, China.
Department of Acupuncture, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
出版信息
Syst Rev. 2022 Jun 22;11(1):128. doi: 10.1186/s13643-022-02007-1.
BACKGROUND
Acupuncture is a widely used alternative and complementary therapy. Functional magnetic resonance imaging (fMRI) is an important technique to explore the underlying mechanism of acupuncture, and the task-based fMRI can reflect the instant effects or sustained effects of acupuncture in the brain. This scoping review aims to summarize the characteristics of acupuncture mechanism studies employing task-based fMRI and conclude a reference for future studies.
METHODS/DESIGN: This review will follow the Guidance for Conducting Scoping Reviews. Eligible articles will be collected from 7 databases (PubMed, Embase, Cochrane, CNKI, WanFang, VIP, and CBM) with the related keywords such as "Acupuncture" and "fMRI"; those articles should be published from January 1, 2000, to December 31, 2021; and the language should be restricted in English or Chinese. Each research step will involve at least two reviewers. The PRISMA-ScR (Preferred Reporting Items for Systemic Reviews and Meta-Analysis Extension for Scoping Reviews) will be used to organize the review. Data will be extracted from the illegible articles, and findings will be presented in tables and narrative form. A descriptive qualitative approach to analysis will be conducted to form the scoping review.
DISCUSSION
This review aims to clarify the extent of acupuncture mechanism studies employing task-based fMRI. It is supposed to make a critical evaluation or propose quality requirements for future studies by summarizing the objectives and designs of eligible studies. What is more, directional suggestions will be provided for further studies.
SCOPING REVIEW REGISTRATION
Open Science Framework https://osf.io/zjrdc/ .
背景
针灸是一种广泛应用的替代和补充疗法。功能磁共振成像（fMRI）是探索针灸潜在机制的重要技术，任务态 fMRI 可以反映针灸在大脑中的即时效应或持续效应。本范围综述旨在总结基于任务的 fMRI 针灸机制研究的特点，并为未来的研究提供参考。
方法/设计：本综述将遵循范围综述指南进行。从 7 个数据库（PubMed、Embase、Cochrane、CNKI、万方、维普和 CBM）中收集符合条件的文章，关键词为“针灸”和“fMRI”；文章应发表于 2000 年 1 月 1 日至 2021 年 12 月 31 日；语言限于英语或中文。每个研究步骤将至少涉及两名评审员。将使用 PRISMA-ScR（系统评价和荟萃分析扩展的首选报告项目用于范围综述）来组织综述。将从难以辨认的文章中提取数据，并以表格和叙述形式呈现研究结果。将采用描述性定性方法进行分析，形成范围综述。
讨论
本综述旨在阐明基于任务的 fMRI 针灸机制研究的范围。通过总结合格研究的目标和设计，对未来的研究进行批判性评价或提出质量要求，并为进一步的研究提供有针对性的建议。
范围综述注册
Open Science Framework https://osf.io/zjrdc/ 。
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