Park Gyusik, Kesserwani Hassan N
Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, USA.
Cureus. 2022 May 17;14(5):e25089. doi: 10.7759/cureus.25089. eCollection 2022 May.
Diabetic striatopathy (DS) is an acute hyperkinetic movement disorder characterized by hemiballismus-hemichorea (HBHC) due to nonketotic hyperglycemia. DS manifests a fascinating interplay between endocrinopathy (diabetes), striatal (putamen, caudate nucleus, globus pallidus) pathology, and a dramatic neurological movement disorder, HBHC. The striking hyperintensity on imaging modalities such as computed axial tomography (CT) scan of the brain and T1-weighted magnetic resonance imaging (MRI) of the brain can mislead the clinician to an erroneous diagnosis of a cerebral hemorrhage and/or ischemic infarct, especially in an acute setting. We present an acute case of DS and outline the natural history, semiology, typical radiological findings, and therapeutic options. With careful and thoughtful analysis, an accurate diagnosis can be exacted, sparing the patient unnecessary anxiety and medical costs.
糖尿病性纹状体病（DS）是一种急性运动亢进性运动障碍，其特征为非酮症高血糖所致的偏身投掷-偏身舞蹈症（HBHC）。DS表现出内分泌病（糖尿病）、纹状体（壳核、尾状核、苍白球）病理改变与严重的神经运动障碍HBHC之间的迷人相互作用。在脑部计算机断层扫描（CT）和脑部T1加权磁共振成像（MRI）等影像学检查中出现的显著高信号，可能会误导临床医生错误地诊断为脑出血和/或缺血性梗死，尤其是在急性期。我们报告一例DS急性病例，并概述其自然病史、症状学、典型影像学表现及治疗选择。通过仔细深入的分析，可以做出准确诊断，避免患者不必要的焦虑和医疗费用。
