Chithrapathra Kasun E, Hewanayake Waruni S, Egodage Samitha, Silva Shehan
Internal Medicine, Colombo South Teaching Hospital, Kalubowila, LKA.
Radiology, Army Hospital, Colombo, LKA.
Cureus. 2023 Sep 19;15(9):e45581. doi: 10.7759/cureus.45581. eCollection 2023 Sep.
Diabetic striatopathy (DS) is a condition occurring in individuals with type II diabetes mellitus (T2DM) where there are abnormal (usually single-sided) bodily movements (hemiballismus-hemichorea (HBHC)). DS involves the interaction between diabetes leading to damage to areas such as the striatum with the development of a noticeable hyperkinetic movement disorder. Here, we present a case of a 72-year-old man with T2DM, ischaemic heart disease, and dyslipidaemia, who presented with involuntary movements of the bilateral upper limbs (the left side more affected than the right) for three weeks along with progressively worsening subtle involuntary movements of the mouth and tongue, with intact speech, swallowing, and gait. The neurological examination revealed high-amplitude intermittent, sudden onset involuntary movements of the bilateral upper limbs, primarily affecting the left side. Based on clinical findings, which were supported by imaging studies, a diagnosis of diabetic striatopathy was made. His presentation was beyond the classical presentation of unilateral involvement seen in HBHC, but with early identification and strict glycemic control, satisfactory improvement of his clinical status was achieved.
糖尿病性纹状体病（DS）是一种发生于2型糖尿病（T2DM）患者的疾病，其特征为出现异常（通常为单侧）身体运动（偏侧投掷症-偏侧舞蹈症（HBHC））。DS涉及糖尿病导致纹状体等区域受损与明显的运动亢进性运动障碍发展之间的相互作用。在此，我们报告一例72岁男性患者，患有T2DM、缺血性心脏病和血脂异常，出现双侧上肢不自主运动（左侧比右侧更严重）3周，同时伴有口部和舌部逐渐加重的细微不自主运动，言语、吞咽和步态正常。神经系统检查发现双侧上肢出现高幅度间歇性、突发的不自主运动，主要影响左侧。基于影像学研究支持的临床发现，诊断为糖尿病性纹状体病。他的表现超出了HBHC中所见的单侧受累的经典表现，但通过早期识别和严格的血糖控制，其临床状况得到了令人满意的改善。
