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开放性活体肝移植术中使用血管吻合器离断肝门和门静脉——一项回顾性队列研究

Hepatic and portal vein transection by vascular stapler in open living donor hepatectomy - A retrospective cohort study.

作者信息

Obed Doha, Jarrad Anwar, Othman Mohammad Ibrahim, Siyam Mahmoud, Bashir Abdalla, Obed Aiman

机构信息

Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover, Germany.

Department of Gastroenterology, Jordan Hospital, Amman, Jordan.

出版信息

Ann Med Surg (Lond). 2022 May 18;78:103823. doi: 10.1016/j.amsu.2022.103823. eCollection 2022 Jun.

DOI:10.1016/j.amsu.2022.103823
PMID:35734708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9206906/
Abstract

BACKGROUND

In an effort to increase donor safety in living donor liver transplantation, the utilization of vascular staplers for the division of the right portal and hepatic veins in patients undergoing right lobe liver donation for living donor liver transplantation (LDLT) was implemented. In here we report our experience with vascular staplers in patients undergoing LDLT and evaluate the subsequent feasibility and safety for donors.

MATERIAL AND METHODS

17 cases of living donor liver transplant were retrospectively analyzed. The right portal vein was transected directly at the bifurcation of the main portal vein, the right hepatic vein was resected directly at the wall of the inferior vena cava using a vascular stapler device.

RESULTS

We registered a complication rate of 41.2% (7 donors). According to the Clavien-Dindo classification, grade II and grade III complications were each observed in 5.9% and grade IIIb complications in 29.4%, whereas catastrophic bleeding, complications with residual disability or the necessity of re-laparatomy did not occur. Upon 6 weeks, all donors were able to return to their previous occupation in fully recovered condition.

CONCLUSIONS

The utilization of vascular staplers in donors during open LDLT presents an encouraging alternative to manual over-sewing of vascular stumps. Apart from its timesaving aspect, the technique reduces the potential risk of life-threatening clamp slippage with subsequent uncontrolled blood loss.

摘要

背景

为提高活体肝移植供体的安全性,在活体肝移植(LDLT)右半肝供肝的患者中,采用血管吻合器离断右门静脉和肝静脉。在此,我们报告我们在LDLT患者中使用血管吻合器的经验,并评估其对供体的可行性和安全性。

材料与方法

回顾性分析17例活体肝移植病例。使用血管吻合器装置在门静脉主干分叉处直接横断右门静脉,在下腔静脉壁处直接切除右肝静脉。

结果

我们记录的并发症发生率为41.2%(7例供体)。根据Clavien-Dindo分类,Ⅱ级和Ⅲ级并发症各占5.9%,Ⅲb级并发症占29.4%,而未发生灾难性出血、残留残疾并发症或再次开腹手术的必要性。6周后,所有供体均能完全康复并恢复原工作。

结论

在开放式LDLT中,供体使用血管吻合器是手动缝合血管残端的一种令人鼓舞的替代方法。除了节省时间外,该技术还降低了危及生命的夹子滑脱及随后失控失血的潜在风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/3ba049de75fe/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/253f4b1c6cc6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/b9fe25d4b68c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/863c70894ab7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/3ba049de75fe/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/253f4b1c6cc6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/b9fe25d4b68c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/863c70894ab7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/361f/9206906/3ba049de75fe/gr4.jpg

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STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery.STROCSS 2021:加强外科学队列研究、横断面研究和病例对照研究报告规范。
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Pure Laparoscopic Donor Hepatectomy: A Multicenter Experience.单纯腹腔镜供肝切除术:多中心经验。
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Laparoscopic donor right hepatectomy in a donor with type III portal vein anomaly: A case report.
腹腔镜下对门静脉Ⅲ型变异供体进行右肝切除术:一例报告
Medicine (Baltimore). 2019 Aug;98(32):e16736. doi: 10.1097/MD.0000000000016736.
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Pure Laparoscopic Living Donor Hepatectomy for Donors With Right Portal Vein Anatomical Variations.针对右门静脉解剖变异供体的纯腹腔镜活体供肝切除术
Liver Transpl. 2019 Sep;25(9):1445-1454. doi: 10.1002/lt.25582. Epub 2019 Jul 8.
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Pure laparoscopic living donor hepatectomy using the Glissonean pedicle approach (with video).经 Glissonean 蒂 approach(附视频)行纯腹腔镜活体供肝切除术。
Surg Endosc. 2019 Aug;33(8):2704-2709. doi: 10.1007/s00464-019-06818-7. Epub 2019 May 13.
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Liver Transpl. 2018 Nov;24(11):1545-1553. doi: 10.1002/lt.25307.
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Middle Hepatic Vein Bleed During Donor Hepatectomy: Technique for Safe Practice.供肝切除术中肝中静脉出血:安全操作技术
J Clin Exp Hepatol. 2017 Dec;7(4):376-377. doi: 10.1016/j.jceh.2017.05.008. Epub 2017 May 19.
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Pure laparoscopic living donor hepatectomy: Focus on 55 donors undergoing right hepatectomy.纯腹腔镜活体供肝切除术:关注 55 例右半肝切除术供者。
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