Oladipo Abiodun, Enwemiwe Victor, Ejeromedoghene Onome, Adebayo Ademola, Ogunyemi Olakunle, Fu Fangfang
Co-Innovation Center for Sustainable Forestry in Southern China, College of Forestry, Nanjing Forestry University, Nanjing 210037, China.
Department of Animal and Environmental Biology, Delta State University, Abraka 330106, Nigeria.
Metabolites. 2022 Jun 10;12(6):534. doi: 10.3390/metabo12060534.
Medicinal plants are rich sources of specialized metabolites that are of great importance to plants, animals, and humans. The usefulness of active biological compounds cuts across different fields, such as agriculture, forestry, food processing and packaging, biofuels, biocatalysts, and environmental remediation. In recent years, research has shifted toward the use of microbes, especially endophytes (bacteria, fungi, and viruses), and the combination of these organisms with other alternatives to optimize the production and regulation of these compounds. This review reinforces the production of specialized metabolites, especially by plants and microorganisms, and the effectiveness of microorganisms in increasing the production/concentration of these compounds in plants. The study also highlights the functions of these compounds in plants and their applications in various fields. New research areas that should be explored to produce and regulate these compounds, especially in plants and microbes, have been identified. Methods involving molecular studies are yet to be fully explored, and next-generation sequencing possesses an interesting and reliable approach.
药用植物是特殊代谢产物的丰富来源，这些代谢产物对植物、动物和人类都非常重要。活性生物化合物的用途广泛，涵盖不同领域，如农业、林业、食品加工与包装、生物燃料、生物催化剂以及环境修复等。近年来，研究已转向利用微生物，特别是内生菌（细菌、真菌和病毒），以及将这些生物体与其他替代方法相结合，以优化这些化合物的生产和调控。本综述强化了特殊代谢产物的生产，尤其是植物和微生物的生产，以及微生物在提高植物中这些化合物产量/浓度方面的有效性。该研究还强调了这些化合物在植物中的功能及其在各个领域的应用。已确定了为生产和调控这些化合物，尤其是在植物和微生物中，应探索的新研究领域。涉及分子研究的方法尚未得到充分探索，而新一代测序则是一种有趣且可靠的方法。
